Cryopreservation, ICSI, Infertility, IVF
Conditions
Brief summary
This multicentre randomized controlled trial will be done to evaluate a new strategy in IVF-ICSI practice that gives that priority to freeze for the embryos and goes to fresh embryo transfer only if at least one set of same quality embryos is available for cryopreservation.
Detailed description
This study will be a non-blind, prospective, double-armed, randomized clinical trial. The study will be conducted at five centers, the Educational Hospital Fertility Unit of Tanta University, the fertility center of Cairo University, the fertility center of Assiut University, the Egyptian Consultants Fertility Center in Tanta, and MRC fertility center in Cairo from May 1st 2019 till the end of the objected number. The study will be conducted in accordance with the Declaration of Helsinki, and all participants should sign a written informed consent before inclusion in the study.
Interventions
PROCEDUREPriority to freeze
Priority for cryopreservation and later on embryo transfer in artificial cycle with endometrium preparation by the exogenous administration of estrogen-progesterone.
PROCEDUREFresh embryo transfer
usual strategy of giving the priority for fresh embryo transfer
Sponsors
Tanta University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
FEMALE
Age
20 Years to 35 Years
Healthy volunteers
No
Inclusion criteria
* Candidates for IVF/ICSI * Presence of good number of embryos \> 5
Exclusion criteria
* Low quality embryos * Low ovarian reserve * Low number of embryos
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Cumulative pregnancy rates | 3 months | The number of pregnant women in both groups after 3 cycles |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Failure of pregnancy | 3 months | Failed ICSI |
Countries
Egypt
Contacts
Primary ContactAyman Dawood, MD
Backup ContactAdel Elgergawy, MD
Outcome results
None listed