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Mri in Evaluation of Cesarean Section Scar Niche

Role of Magnetic Resonance Imaging in Evaluation of Uterine Cesarean Section Scar Niche

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT03911622
Enrollment
30
Registered
2019-04-11
Start date
2019-04-30
Completion date
2020-09-30
Last updated
2019-04-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cesarean Section; Dehiscence

Brief summary

To evaluate cesarean section scar and the lower uterine segment in non pregnant woman by MRI to : 1. Assess the clinical symptoms like postmenstrual spotting or prolonged menstrual bleeding, dysmenorrhea, chronic pelvic pain and dyspareunia and its relation to the presence of cesarean scar defects and its characteristics . 2. development of scoring system and correlating it with the symptoms .

Detailed description

With increasing cesarean section rate nowadays, the risks of cesarean scar defect (CSD) should increase. CSD is defined by ultrasound imaging as a triangular hypoechoic defect in the myometrium at the site of the previous cesarean section scar. However, patients with CSD are sometimes asymptomatic. Yet, some patients with CSD can have symptoms of abnormal uterine bleeding, pelvic pain, infertility, uterine rupture, and potential risks of adverse pregnancy outcome .There is an association between the size of a niche and postmenstrual spotting. women with a history of CS, the depth and shape of the niche were not significant factors, while a larger niche volume was described in women with postmenstrual spotting. in women with gynecological symptoms, the niches were significantly wider in women with postmenstrual spotting, dysmenorrhea or chronic pelvic pain, and the prevalence of postmenstrual spotting or prolonged menstrual bleeding was higher with a larger diameter of the niche .Magnetic resonance imaging (MRI) has recently shown a promise tool for evaluation of uterine scar thickness. As opposed to ultrasonography (USG), which is the current gold standard for this purpose, MRI reduces observer dependence and has a superior multiplanar capability. MRI can be used for assessment of lower uterine segment. It provides accurate tissue characterization, independent of patient body mass index .

Interventions

DEVICEMRI

medical device that is used as an imaging tool for soft tissues

Sponsors

Assiut University
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
FEMALE
Age
18 Years to 45 Years
Healthy volunteers
No

Inclusion criteria

1. previous lower uterine segment cesarean section before . 2. At least 6 months after the last cesarean section . 3. still regularly menstruating . 4. Absence of other gynecological disease or intrauterine lesions like endometriosis , uterine fibroid .

Exclusion criteria

1. Post menopausal women . 2. hysterectomy . 3. Presence of other gynecological disease like endometriosis , uterine fibroids . 4. any general contraindication to MRI as presence of any paramagnetic substance as pacemakers or in severely ill patients or those with claustrophobia, arrhythmic patients . 5. intrauterine devices . 6. bleeding tendency.

Design outcomes

Primary

MeasureTime frameDescription
MRI pelvis examination (sagittal T2WI ) using 1.5 tesla system Torso phased-array body coil with the patient in the supine position and a moderately full urinary bladderbaseline* Pre-designated standard protocols were followed consisting of T1-weighted (T1W) and T2-weighted (T2W) imaging sequences in axial and sagittal planes remaining perpendicular to the long axis of the scar * The scar site will be identified as the thinnest portion of LUS and having the lowest signal intensity on T2W imaging.

Secondary

MeasureTime frameDescription
clinical evaluationbaselineasking patients about clinical symptoms like postmenstrual spotting , secondary infertility and chronic pelvic pain in order to correlate them with the scar criteria collected by MRI
transabdominal and transvaginal ultrasound examinationbaselinemeasuring scar depth in mm .

Contacts

Primary Contactkerolos wagdy
kerowagdy25@gmail.com01284296866

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026