Diabetes Mellitus, Type 2, Periodontal Disease
Conditions
Brief summary
the aim of this study was to assess serum levels of high sensitivity c reactive protein in periodontitis patients with and without type 2 diabetes in a trial to analyze its prognostic effect following non-surgical periodontal therapy.
Detailed description
Periodontitis and diabetes are chronic disorders with a two-way correlation as they can both stimulate an inflammatory response with subsequent formation of inflammatory mediators and cytokines. C reactive protein is an inflammatory plasma marker having a role in the systemic reaction to inflammation. thus, our aim in the current study was to evaluate serum levels of high sensitivity c reactive protein in periodontitis patients with and without type 2 diabetes in a trial to analyze its prognostic effect following non-surgical periodontal therapy. A total of 60 patients were enrolled in this study. ELISA was used for determination of hs- CRP. Non- surgical periodontal therapy was carried out for all periodontitis patients.
Interventions
PROCEDUREScaling and root planing
Supra and subgingival scaling and root planing.
Sponsors
Cairo University
Study design
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
DIAGNOSTIC
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Healthy volunteers
Yes
Inclusion criteria
1. Diabetic patients type 2 2. Periodontitis patients
Exclusion criteria
1. Smokers 2. Pregnant females
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| clinical attachment level | 3 months | gain in clinical attachment level |
Countries
Egypt
Outcome results
None listed