Obese, Elevated Blood Pressure
Conditions
Brief summary
Obesity is associated with progressive decreases in arterial health and function. It is crucial to prevent or reduce the negative effects of aging on the vasculature by implementing appropriate lifestyle interventions, such as exercise training. We examined the effects of a Mat Pilates training (MPT) regimen on arterial stiffness (pulse wave velocity, PWV), blood pressure (BP), wave reflection (AIx) and endothelial function in obese premenopausal women with elevated BP.
Detailed description
Using a parallel experimental design, participants were randomly assigned to either MPT (n=14) or non-exercising control group (n=14) for 12 weeks. Participant in the MPT group trained 3 days/week . Participants' brachial to ankle PWV (baPWV), systolic and diastolic BP, AIx, plasma NO levels were measured at baseline and after 20 weeks of their assigned intervention.
Interventions
This group completed 12-weeks of training
Sponsors
Study design
Eligibility
Inclusion criteria
* body mass index 30-40 kg/m2 * \<1 h of regular exercise per week in the previous year * systolic/diastolic BP: 120-129mm Hg systolic BP and ˂ 80 mm Hg for diastolic BP * Nonsmokers
Exclusion criteria
* body mass index ˂30 and ≥40 kg/m2 * chronic diseases * taking oral contraceptives * pregnancy
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Arterial Stiffness | 12 weeks | via Pulse Wave Velocity |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Systolic and Diastolic Blood Pressure | 12 weeks | Automatic BP monitor |
| Pressure Wave Reflection | 12 weeks | via Augmentation Index |
| Endothelial Function | 12 weeks | via plasma nitric oxide |
Countries
United States