Healthy
Conditions
Keywords
protein source, hypertrophy, resistance training, plant-based protein, omnivorous
Brief summary
Dietary protein consumption maximizes the anabolic response during resistance training (RT) by triggering muscle protein synthesis and providing the indispensable amino acids for a net positive protein balance. Leucine is considered the key amino acid in this process, suggesting that differences in protein quality may influence RT-induced gains in muscle mass and strength. In general, plant-based protein sources have lower leucine concentrations than animal-based protein sources and human skeletal muscle. In this respect, despite acute evidence on lower anabolic properties of plant- vs. animal-based protein, the effects of an exclusive plant-based dietary protein diet on RT-induced adaptations are currently unknown.
Interventions
supplementation individually adjusted to 1.6g/kg/day
supplementation individually adjusted to 1.6g/kg/day
Sponsors
Study design
Eligibility
Inclusion criteria
* Healthy young men * Vegans ≥ 1 y or omnivorous subjects * Physically active but no resistance-trained subjects * Without any chronic injury that impairs resistance training performance * Protein intake \> 0.8 g/protein/kg body weight
Exclusion criteria
* Use of creatine or beta-alanine supplements for the last 3 months * Use of proteins and/or amino acids supplements for the last 1 month * Engagement in specific dietary restrictions * Previous use of anabolic steroids * Engagement in any training program
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Muscle cross-sectional area | 12 weeks | assessed by mode-B ultrasound |
| Muscle strength | 12 weeks | assessed by leg-press one-maximum-repetition |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Leg lean mass | 12 weeks | assessed by Dual-energy X-ray absorptiometry |
| fiber cross-sectional area | 12 weeks | assessed by muscle biopsy (vastus lateralis) |
Countries
Brazil