Evaluation of the Effect of Corticotomy and Low Level Laser Therapy on Orthodontic Tooth Movement

Evaluation of the Combined Effect of Corticotomy and Low Level Laser Therapy on the Rate of Orthodontic Tooth Movement: Split Mouth Randomized Clinical Trial

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT03906084

Enrollment

Registered

2019-04-08

Start date

2015-04-30

Completion date

2018-05-31

Last updated

2019-04-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dental Malocclusion

Brief summary

The aim of the present study was to compare, a standard efficient technique in accelerating OTM as surgical corticotomy as a gold standard versus surgical corticotomy combined with LLLT in an attempt for further acceleration of OTM.

Detailed description

The study design was a randomized split mouth design to compare, clinically and radiographically, between the two interventions (Corticotomy and Laser versus Corticotomy only) by assessing the rate of maxillary canine retraction achieved in 4 months. Secondary outcomes were to evaluate 1st maxillary molar anchorage loss, changes in tipping, torque and rotations values of maxillary canine and 1st molar. In addition, the impact of both interventions on root resorption was assessed. The present study was carried on 16 female patients. All patients required maxillary 1st premolar extraction and subsequent maxillary canine retraction.

Interventions

PROCEDURECorticotomy and low laser therapy

Corticotomy is carried out under local anesthesia followed by low-intensity laser therapy that is started on the selected experimental side on the same day as placement of the coil spring

PROCEDURECorticotomy facilitated Orthodontics

Corticotomy is carried out under local anesthesia in right side.

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

SINGLE (Outcomes Assessor)

Masking description

Single Blind Endpoint Classification: Efficacy Study

Eligibility

Sex/Gender

FEMALE

Age

17 Years to 25 Years

Healthy volunteers

Yes

Inclusion criteria

1. Post pubertal patients with age more than 17 years. 2. Class I or Class II (Angles' classification) malocclusion cases requiring 1st premolar extraction with moderate anchorage.

Exclusion criteria

1. Patients having missing permanent canine teeth in maxillary arch. 2. History of trauma or root canal treatment in maxillary canines. 3. History of previous orthodontic treatment. 4. History of hormonal disorder or syndrome.

Design outcomes

Primary

Measure	Time frame	Description
Rate of canine retraction	4 months	Rate of canine retraction using a digital caliper, units of mm, readings extracted from digital models reading each month.

Secondary

Measure	Time frame	Description
Root resorption	after 4 months from start of clinical trial	Root resorption using CBCT in mm after the end of canine retraction period (at the end of 4 months)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026