Foreign Bodies, Tumor, Stenosis of Trachea, Bronchus
Conditions
Brief summary
The aim of this study is to evaluate the effect of high-flow nasal cannula oxygen administration on maintenance of oxygenation and removal of carbon dioxide during apnoeic period in pediatric patients undergoing general anesthesia with rigid bronchoscopy
Interventions
DEVICEOptiflow
supply of oxygen at 2 L / min/ kg through Optiflow
Sponsors
Yonsei University
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
No minimum to 7 Years
Healthy volunteers
No
Inclusion criteria
* 1\. Patients undergoing general anesthesia with stent placement or bougination, biopsy or removal of a foreign body or a mass through a rigid bronchoscope * 2\. Patients aged 7 or younger who meet American Society of Anesthesiologists (ASA) physical class 2-4
Exclusion criteria
* 1\. Patients undergoing extracorporeal membrane oxygenation (ECMO) * 2\. Patients with active nasal bleeding), severe nasal obstruction, recent nasal trauma of surgery * 3\. Patients with current maxillofacial trauma or basal skull fracture * 4\. Patients with active nasal bleeding), severe nasal obstruction, recent nasal trauma of surgery * 5\. Extremely low birth weight infant and premature infant less than 28 weeks gestation age * 6\. Patients who had previously undergone rigid bronchoscopy / surgery * 7\. If the parent of subject includes a person who can not read the written consent (eg, illiterate, foreigner, etc.)
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Hypoxia occurs the first time | The time taken to reach the point at which peripheral oxygen saturation fell below 90% for the first time immediately after the onset of apnea intraoperatively. | The time taken to reach the point at which peripheral oxygen saturation fell below 90 for the first time immediately after the onset of apnea |
| the lowest oxygen saturation | apnea period during the rigidbroscopic procedure/surgery | the lowest value of oxygen saturation measured percutaneously at extremity. |
| Occurence of hypoxic event | apnea period during the rigidbroscopic procedure/surgery | Occurence of hypoxic event: Presence or absence of hypoxia(peripheral oxygen saturation fell below 90% ) during rigid bronchoscopy |
Secondary
| Measure | Time frame |
|---|---|
| End-tidal carbon dioxide partial pressure | end-tidal CO2 partial pressure after 3 consecutive breaths after intubation or insertion of laryngeal mask following end of apnea during intraoperative period. |
| Arterial oxygen / carbon dioxide partial pressure | shortly before start of apnea (within 30 seconds) and shortly after end of apnea (within 30 seconds) |
Countries
South Korea
Outcome results
None listed