The Heidelberg Engineering SPECTRALIS Macular Precision and Agreement Study

Inclusion criteria

Inclusion All Eye Populations * Age 22 years or older * Able and willing to undergo the test procedures, sign informed consent, and follow instructions * Able to fixate * Refraction between +6 and -6 diopters and astigmatism ≤ 2 diopters. * Axial length ≤ 26.0 mm Exclusion All Eye Populations * Subjects unable to read or write * Ocular media is not sufficiently clear to obtain acceptable quality images * Physical inability to be properly positioned at the study devices or eye exam equipment Inclusion Normal Population * Eyes without prior intraocular surgery bilaterally (except cataract surgery and LASIK) * Intraocular pressure ≤ 21mmHg * Best corrected visual acuity ≥ 20/40 * Clinically normal appearance of the optic disc, with normal appearing neuroretinal rim with respect to color and shape, and clinically normal appearing posterior pole * Both eyes must be determined to be normal, as determined by an investigator Exclusion Normal Population * Subjects with vitreal, retinal or choroidal conditions or disease of the optic nerve. Subjects may have diabetes but cannot have diabetic retinopathy. * History of glaucoma (not including family history) * Unreliable visual field as determined by the manufacturer's recommendations of: Fixation losses \> 20%, False Positives \> 33%, False Negatives \> 15% -Visual field defects consistent with glaucomatous optic nerve damage based on at least one of the following two findings: On pattern deviation (PD), there exists a cluster of 3 or more points in an expected location of the visual field depressed below the 5% level, at least 1 of which is depressed below the 1% level; Glaucoma hemi-field test outside normal limits Inclusion Glaucoma Population * Subjects who have a glaucoma diagnosis without prior non-glaucoma related intra-ocular surgery (except cataract surgery and LASIK) * Glaucomatous optic nerve damage as evidenced by any of the following optic disc or retinal nerve fiber layer structural abnormalities: Diffuse thinning, focal narrowing, or notching of the optic disc rim, especially at the inferior or superior poles with or without disc hemorrhage; Localized abnormalities of the peripapillary retinal nerve fiber layer, especially at the inferior or superior poles; or Optic disc neural rim asymmetry of the two eyes consistent with loss of neural tissue * Visual field defects consistent with glaucomatous optic nerve damage based on at least one of the following two findings: * On pattern deviation (PD), there exists a cluster of 3 or more points in an expected location of the visual field depressed below the 5% level, at least 1 of which is depressed below the 1% level; Glaucoma hemi-field test outside normal limits. * Best corrected visual acuity ≥ 20/40 Exclusion Glaucoma Population * Subjects with presence of any ocular pathology other than Glaucoma in the study eye (cataracts are acceptable) * Unreliable visual field as determined by the manufacturer's recommendations of: Fixation losses \> 20%, False Positives \> 33%, False Negatives \> 15% Inclusion Retina Population * Subjects who have a retinal condition diagnosis without prior non-retinal related intra-ocular surgery (except cataract surgery and LASIK). * Intraocular pressure ≤21mmHg * Best corrected visual acuity ≥20/400 Exclusion Retina Population -Subjects with presence of any ocular pathology other than retinal conditions in the study eye (cataracts are acceptable)