Herpes Zoster
Conditions
Keywords
post-zoster neuralgia, Herpes Zoster-related complications
Brief summary
This retrospective analysis is to investigate patients' history and clinical presentation in Herpes Zoster (HZ), Zoster-related complications, post-Zoster neuralgia and Herpes Zoster management in order to improve the management of HZ patients, to refine HZ-vaccination strategies and elucidate cost factors of HZ in in the setting of a university hospital in Switzerland generally and in a dermatology department specifically.
Interventions
retrospective report review of HZ patients treated between 2005 and 2018 in the Department of Dermatology at the University Hospital Basel
Sponsors
University Hospital, Basel, Switzerland
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Inclusion criteria
* Reports of patients with HZ at University Hospital Basel between 2004-2018
Exclusion criteria
* rejection to use patient data
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Evaluation of patients' history | single time point assessment at baseline | Free text evaluation of patients' history (age, sex, comorbidities, immunosuppression, obesity, human immune deficiency Virus (HIV), profession, current medication, vaccinations, seasonal occurence of HZ, history of Varicella Zoster virus (VZV) infection |
| Description of the clinical presentation of HZ | single time point assessment at baseline | Free text description of the clinical presentation of HZ (localisation, dermatomes affected), Zoster-related acute pain |
| Evaluation of zoster-related complications | single time point assessment at baseline | Free text evaluation of zoster-related complications (ophthalmic zoster, generalised HZ, Ramsay-Hunt syndrome, zoster meningoencephalitis) |
| Evaluation of the herpes zoster management | single time point assessment at baseline | Free text evaluation of the herpes zoster management (local (antiviral) treatment, systemic antiviral and other treatments, number of revisits, average treatment-related costs, hospitalisations (rate, duration) |
| Assessment of post-zoster neuralgia | single time point assessment at baseline | Free text assessment of post-zoster neuralgia (annual incidence, treatment options used) |
| Evaluation of zoster and pregnancy | single time point assessment at baseline | Free text evaluation of zoster and pregnancy (incidence, time of pregnancy, pregnancy outcomes and complications) |
Countries
Switzerland
Outcome results
None listed