Anesthesia, Peroperative Complication
Conditions
Brief summary
Protective ventilation decreased morbidity and mortality in adults' patients and is now a standard of care in intensive care unit and in anesthesiology. In children, there is no evidence in the literature to recommend protective ventilation during anaesthesia. Moreover the ratio of instrumental dead space to tidal volume is higher in children than in adults. Therefore, it is difficult to propose an optimal tidal volume for all children. The objective of this study is to evaluate the use of alveolar ventilation (estimated by the volumetric capnography) in children under anesthesia. The hypothesis is that in children, alveolar ventilation reported to ideal body weight is a constant to maintain normocarbia, unlike the tidal volume.
Interventions
OTHERAlveolar ventilation monitoring estimated by the capnographic ventilation
Children are monitored using end-tidal CO2, Transcutaneous CO2 and volumetric capnographic. Respiratory rate is set using textbooks and guidelines (pediatric advanced life support). The physician in charge adapts the volume to target a CO2 between 38 and 42 mmHg. Data are recorded after a stabilization period of at least 5 minutes.
Sponsors
Hospices Civils de Lyon
Study design
Observational model
CASE_ONLY
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
2 Months to 12 Years
Healthy volunteers
No
Inclusion criteria
* Children aged \< 12 and * Weight between 5 and 40kg * General anesthesia * Non-opposition of parents or legal guardians
Exclusion criteria
* History of bronchodysplasia or laryngo tracheo malacia, cyanotic heart disease or neuromuscular disease * Airleaks \> 10% * Bronchospasm during anesthesia
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Determination of target alveolar minute volume to maintain normocapnia in children without mechanical ventilation. | 5 minutes after hemodynamic and ventilatory stabilization period | The minute alveolar ventilation estimated by the volumetric capnography reported to the ideal body weight based on 100 breaths (expressed in ml/Kg/min). |
Countries
France
Outcome results
None listed