Cardiac Output, Critically Ill
Conditions
Brief summary
This study evaluates the role of arterial tone in the accuracy of cardiac output (CO) measurement by Pressure Recording Analytical Method (PRAM). Patients receiving noradrenaline who need for clinical reason to change the noradrenaline dose will be enrolled. We use echocardiography as reference method of CO measurement.
Detailed description
Pressure Recording Analytical Method (PRAM) is an arterial pulse contour analysis method for CO measurement. As it is an uncalibrated method, one possible reason for its inaccuracy is rapid changes in arterial tone.
Interventions
DEVICEMostCare
CO measurement using echocardiography and PRAM before and after noradrenaline dose change due to clinical reason
Sponsors
Università Politecnica delle Marche
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* invasive blood pressure monitoring on site * need to start or change the dose of noradrenaline infusion for clinical reason
Exclusion criteria
* age \<18 * arrhythmia * severe valvular insufficiency * pregnancy * low quality arterial signal
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Changes of cardiac output after variation of noradrenaline dose: ECO versus PRAM | Before and 30 minutes after noradrenaline dose variation | Agreement between echocardiography and PRAM in CO measurement during arterial tone changes induced by different dose of noradrenaline |
Countries
Italy
Outcome results
None listed