Influenza, Human
Conditions
Brief summary
The purpose of this study is to compare the efficacy of 5-day versus 10-day oseltamivir prophylactic treatment in patients who had been exposed to influenza.
Interventions
DRUGOseltamivir Oral Capsule for 5 days post-exposure
Patients will receive oseltamivir for 5 days after last influenza exposure.
DRUGOseltamivir Oral Capsule for 10 days post-exposure
Patients will receive oseltamivir for 10 days after last influenza exposure.
Sponsors
University Medical Centre Ljubljana
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* 18 years or older * exposure to influenza during hospitalization * risk factors for influenza complications * consent for participation obtained
Exclusion criteria
* younger than 18 years * hematological malignancy * hospitalized in intensive care unit * refusal to participate
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Occurrence of influenza like illness 10 days after oseltamivir prophylactic therapy | 10 days after oseltamivir prophylactic therapy | Experiencing influenza like illness as self assessed by a patient and/or as assessed by a medical doctor while on prophylaxis with oseltamivir and during the following 10 days. |
Countries
Slovenia
Outcome results
None listed