PCOS
Conditions
Keywords
PCOS, Vitamin D, Supplementation, Ovulation, Pregnancy
Brief summary
To assess whether Vitamin D supplementations for patients with polycystic ovary syndrome in conjunction with clomiphene citrate are beneficial or not
Detailed description
This study is double blinded randomized controlled study conducted at Tanta University hospitals in the period from April 2019 to March 2022. Patients and methods: One hundred twelve patients were recruited and randomly allocated into 2 groups; study group with Vitamin D supplementation and control group without Vitamin D supplementation.
Interventions
DRUGVitamin D
receive 6000iu daily for 8 weeks
DRUGPlacebo Oral Tablet
placebo for the same period
Sponsors
Tanta University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Caregiver)
Masking description
Both patients and gynecologists were binded
Intervention model description
The 2 groups will be treated at the same time
Eligibility
Sex/Gender
FEMALE
Age
20 Years to 35 Years
Healthy volunteers
No
Inclusion criteria
* PCOS * Infertile * Vitamin D deficient
Exclusion criteria
* Age less than 20 and more than 35 * Non PCOS patients * Obese patients * Previous ovarian surgery * Previous oophrectomy of one ovary
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Ovulation rate | 3 months | Number of mature follicles obtained |
| Pregnancy rate | 3 months | Number of patients who get pregnant |
Countries
Egypt
Outcome results
None listed