Arthroplasty
Conditions
Keywords
hip arthroplasty, hip prosthesis resection, first implantation, wear particles
Brief summary
Hip arthroplasty is a treatment widely used in most inflammatory, traumatic and degenerative conditions of this joint. The longevity of implants may be disappointing in some cases, despite the promising results obtained during in vitro simulations. Early loco-regional or systemic dissemination, known since the 1990s, of wear particles from these prosthesis may reduce their life span. The analysis of the particles in the synovial fluid and in the articular tissues by electron microscopy after digestion or directly by optical microscopy, will improve the knowledge on the mechanisms of wear. This category 3 study is based on the case-control model and will be conducted in a national reference center (hospital la Croix-Rousse- Lyon). It will include a population of adult patients.
Interventions
PROCEDUREhip prosthesis removed metal / polyethylene, simple mobility
Patients are hospitalized in order to change their hip prosthesis at the hospital la Croix-Rousse in Lyon. Patients have to complete before the surgery a survey on occupational and environmental exposures to mineral dust. The prosthesis removed is composed by metal/polyethylene. It's a simple mobility The aim is to define the types of particles that cause the most tissue inflammation
PROCEDUREhip prosthesis removed metal / polyethylene, double mobility
Patients are hospitalized in order to change their hip prosthesis at the hospital la Croix-Rousse in Lyon. Patients have to complete before the surgery a survey on occupational and environmental exposures to mineral dust. The prosthesis removed is composed by metal/polyethylene. It's a double mobility. The aim is to define the types of particles that cause the most tissue inflammation
PROCEDUREhip prosthesis removed ceramic/ polyethylene, simple mobility
Patients are hospitalized in order to change for their hip prosthesis at the hospital la Croix-Rousse in Lyon. Patients have to complete before the surgery a survey on occupational and environmental exposures to mineral dust. The prosthesis removed is composed by ceramic/polyethylene. It's a simple mobility. The aim is to define the types of particles that cause the most tissue inflammation
PROCEDUREhip prosthesis removed ceramic/ polyethylene, double mobility
Patients are hospitalized in order to change their hip prosthesis at the hospital la Croix-Rousse in Lyon. Patients have to complete before the surgery a survey on occupational and environmental exposures to mineral dust. The prosthesis removed is composed by ceramic/polyethylene. It's a double mobility. The aim is to define the types of particles that cause the most tissue inflammation.
PROCEDUREPrimary implanted hip prosthesis
Patients are hospitalized in order to have a first hip prosthesis at the hospital la Croix-Rousse in Lyon. Patients have to complete before the surgery a survey on occupational and environmental exposures to mineral dust. The patients will be received a first prosthesis.
PROCEDUREhip prosthesis removed metal/metal
Patients are hospitalized in order to change their hip prosthesis at the hospital la Croix-Rousse in Lyon. Patients have to complete before the surgery a survey on occupational and environmental exposures to mineral dust. The prosthesis removed is composed by metal/metal. The aim is to define the types of particles that cause the most tissue inflammation
PROCEDUREhip prosthesis removed ceramic/ceramic
Patients are hospitalized in order to change their hip prosthesis at the hospital la Croix-Rousse in Lyon. Patients have to complete before the surgery a survey on occupational and environmental exposures to mineral dust. The prosthesis removed is composed by ceramic/ceramic. The aim is to define the types of particles that cause the most tissue inflammation
Sponsors
MINAPATH Développement
Hospices Civils de Lyon
Study design
Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Adult patient, * Patient including French, * Patient witness: to be hospitalized in the orthopedic department of the Croix-Rousse hospital for a first hip prosthesis * Patient test: to be hospitalized in the orthopedic department of the Croix-Rousse hospital for the removal of a hip prosthesis
Exclusion criteria
* Patient protected by law (guardianship, curatorship, safeguard of justice). * Pregnant or lactating woman * Patient with suspicion of infection on prosthesis * Patient opposing his participation in the study
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| types of particles that cause the most tissue inflammation | day of surgery | Types of wear particles most found in patients whose tissues are classified as inflammatory. The particles can be classified by size, shape, material and type of original prosthesis. |
Countries
France
Outcome results
None listed