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Ocular Findings of Polycystic Ovary Syndrome

Ocular Surface Disease Test Results, Corneal Biomechanical Properties, and Structural Parameters in Patients With Polycystic Ovary Syndrome

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT03896841
Enrollment
38
Registered
2019-04-01
Start date
2013-03-17
Completion date
2018-03-30
Last updated
2019-04-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Polycystic Ovary Syndrome

Brief summary

Purpose: This study aimed to compare the ocular surface disease test results, anterior segment parameters, and ocular response analyzer (ORA) findings of polycystic ovary syndrome (PCOS) patients with those of healthy reproductive age female controls.

Interventions

OTHERObservation

Ocular Findings Observations

Sponsors

Istanbul Medeniyet University
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
FEMALE
Age
19 Years to 43 Years
Healthy volunteers
Yes

Inclusion criteria

* premenopausal with PCOS

Exclusion criteria

* patients with external ocular disease other than dry eye complaints, * use of topical drops that can affect the tear film layer, * contact lens use histories, * those who received hormone therapy for 6 months, * those who have systemic medication or systemic disease that may affect the tear film layer and reproductive physiology, * previous eye surgeries, * smokers and alcohol users, * those having diseases (Cushing's syndrome or androgen-secreting tumors) causing similar clinical findings.

Design outcomes

Primary

MeasureTime frameDescription
Comparison of the anterior segment parameter results (Pentacam).1 yearmeasurement of the central corneal thickness.
Comparison of the corneal biomechanical parameter results (ocular response analyzer).1 yearmeasurement of the corneal hysteresis (CH).

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026