Beta-Thalassemia
Conditions
Brief summary
to study the frequency and pattern of dermatological abnormalities in egyptian childern with beta thalassemia.relationof abnormalities to duration of disease and frequency of transfusion
Detailed description
thalassemia refers to agroup of inherited disease characterized by decreased or absent synthesis of normal globin .skinvdisorders are usually neglected and frequently underdiagnosed among these patients.skin disease specially pruritus and xerosis are observed highly frequently in patients with beta-thalassemia.pityriasis alba is arelatively common skin disorder.the trophic skin changes and leg ulcers occurred after the age of 15 years
Interventions
DEVICEthalassemia
thalassemic patient use chelator and thaladssemic patient with frequent blood transfusion
Sponsors
Assiut University
Study design
Observational model
OTHER
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
2 Years to 18 Years
Healthy volunteers
Yes
Inclusion criteria
Inclusio2n Criteria: * clinical diagnosis of dermatological abnormalities in thalassemic patient. must be on chelator
Exclusion criteria
* patient with other hemolytic anemia. childern with any abnormalities prior to the diagnosis of thalassemi
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| The percentage of patients with dermatological disorders due to iron overload Iron overload cause dermatological abnormalities | one month | the number of patients who develop any dermatological disorder as a result of iron overload after frequent blood transfusion |
Contacts
Primary ContactAlsayed khalil Abd elkareem, Professor
Backup ContactMostafa Mohamed, Lecturer
Outcome results
None listed