Coronary; Ischemic, STEMI
Conditions
Brief summary
335 of patients with STEMI treated by primary PCI were assayed for PTX3 measurement by ELISA method. The angiographic and clinical outcomes were evaluated according to the PTX3 concentration.
Detailed description
335 of patients with STEMI treated by primary PCI were assayed for PTX3 measurement by ELISA method using human PTX3 kit. Blood was drawn at the emergency department before primary PCI. The angiographic and clinical outcomes were evaluated and analyzed according to the PTX3 concentration. The angiographic outcome were thrombus grade on initial angiogram and final TIMI flow. The clinical outcome were ECG resolution after primary PCI and all-cause death at 30 days. The plasma PTX3 concentration was then compared based on the outcomes.
Interventions
OTHERPlasma PTX3 concentration
Long pentraxin 3, thrombus burden, final TIMI flow, ST segment resolution, STEMI, primary PCI
Sponsors
Indonesian Cardiovascular Research Center
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
* Patients with acute STEMI with symptom onset \<12 h undergoing primary PCI
Exclusion criteria
* Acute STEMI patients who received fibrinolytic therapy
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| The proportion of thrombus grade 4&5 and final TIMI flow <3 | Intraprocedure | PTX3 concentration was compared based on the outcome |
Countries
Indonesia
Outcome results
None listed