Arsenic Poisoning Chronic, Malnutrition, Child
Conditions
Brief summary
Early life malnutrition is associated with later life health problems, Particularly Stunting, which is a height-for-age Z score less than -2 standard deviation of World Health Organization median.Underweight is weight-for-age Z score less than -2 standard deviation of World Health Organization median. Wasting is weight -for- height Z score less than -2 standard deviation of World Health Organization median.
Detailed description
prevalence of under-five stunting, wasting and underweight are 21% and , 8% and 6% respectively in Egyptian Demographic Health Survey 2014. The main risk factors for growth restriction in children are maternal under nutrition during pregnancy, lack of exclusive breastfeeding, inappropriate complementary feeding and micronutrient intake and high prevalence of enteric infections. However, other environmental exposures may also play a role in growth restriction . High concentrations of Arsenic, lead and cadmium in placenta are associated with poor fetal out come and low birth weight. Arsenic crosses the placenta causing suppression of insulin-Like Growth Factor 1. When breastfeeding is exclusive, infants are unlikely to be exposed to Arsenic by other routes of exposure such as external foods, drinking water and foods made at home using Arsenic contaminated water. Rational of the study. Improvement of under-five nutritional status is a global target. Although the exposure to arsenic has increased globally, it's impact on nutritional status has seldom been investigated.
Interventions
DIAGNOSTIC_TESTarsenic exposure
analysis of hair samples for Arsenic using Agilent graphite tube atomizer 120
Sponsors
Assiut University
Study design
Observational model
CASE_CONTROL
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
FEMALE
Age
2 Years to 5 Years
Healthy volunteers
Yes
Inclusion criteria
female children from 2 to 5 years
Exclusion criteria
Severely ill children other than severely malnourished. * Children with congenital anomaly. * Relatives.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Chronic Arsenic Exposure of Under Five Children | one year | Hair samples collected from participating children will be analyzed for Arsenic using Agilent graphite tube atomizer (GTA) 120 |
| weight measurement | one year | weight in kilograms will be measured to all participating children |
| height measurement | one year | height in meters will be measured to all participating children |
Countries
Egypt
Contacts
Primary ContactEman Morsy, professor
Backup ContactMedhat Araby, assis. prof.
Outcome results
None listed