Bronchus Tumour, Foreign Bodies, Stenosis Trachea, Tumor
Conditions
Brief summary
The aim of this study is to evaluate the effect of high-flow nasal cannula oxygen administration on apnea in patients undergoing general anesthesia with rigid bronchoscopy compared with standard anesthesia methods.
Interventions
DEVICEOptiflow ™
supply of 100 % of oxygen at 70 L / min through Optiflow ™ (Fisher and Paykel Healthcare Limited, Auckland, New Zealand) plus standard oxygen supply through rigid bronchoscope during apnea period.
Sponsors
Yonsei University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
NONE
Masking description
triple (Participant, Care Provider, investigator)
Intervention model description
A prospective Randomized, open label Trial
Eligibility
Sex/Gender
ALL
Age
19 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* 1\. Patients undergoing general anesthesia with stent placement or bougination, biopsy or removal of a foreign body or a mass through a rigid bronchoscope * 2\. Patients aged 19 or older who meet American Society of Anesthesiologists (ASA) physical class 2-4
Exclusion criteria
* 1\. Patients with dementia or cognitive impairment * 2\. pregnant women * 3\. Patients undergoing extracorporeal membrane oxygenation (ECMO) * 4\. Patients with active nasal bleeding), severe nasal obstruction, recent nasal trauma of surgery * 5\. Patients with current maxillofacial trauma or basal skull fracture * 6\. Patients who had previously undergone rigid bronchoscopy / surgery * 7\. If the subject includes a person who can not read the written consent (eg, illiterate, foreigner, etc.)
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| the lowest oxygen saturation | apnea period during the rigidbroscopic procedure/surgery | the lowest value of oxygen saturation measured percutaneously at extremity. |
Secondary
| Measure | Time frame |
|---|---|
| Hypoxia occurs the first time | intraoperative (The time taken to reach the point at which peripheral oxygen saturation fell below 90 for the first time immediately after the onset of apnea) |
| End-tidal carbon dioxide partial pressure | Intraoperative (end-tidal CO2 partial pressure after 3 consecutive breaths after intubation or insertion of laryngeal mask following end of apnea) |
| Arterial oxygen / carbon dioxide partial pressure | shortly before start of apnea (within 30 seconds) |
| hypoxemia related surgical interruptions | 4) hypoxemia related surgical interruptions during apneic period |
Countries
South Korea
Outcome results
None listed