Radial Artery Injury
Conditions
Keywords
transradial catheterisation, radial artery spasm
Brief summary
The investigators will investigate whether administration of Nitroglycerin (NTG) as spasmolytic regimen reduces the incidence of moderate to severe radial artery spasm (RAS) in patients undergoing transradial catheterization in radial center.
Detailed description
Patients will be randomized to receive either 200 microgram NTG or placebo (saline) at the beginning of the procedure soon after radial sheath placement. The operators will be blinded to both assignment. The primary outcome is the incidence of moderate to severe RAS evaluated by the operators during the radial procedure. Both NTG and placebo will be administered using an identical syringe to keep the operators blinded to the treatment allocation. Radial angiogram is mandatory to measure the diameter of both radial and ulnar arteries. Doppler ultrasound of the radial artery will be examined at the day after the procedure.
Interventions
DRUGNTG 1 MG/ML Injectable Solution
administered after sheath placement
Sponsors
Hermina Heart Center Kemayoran
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
SINGLE (Subject)
Intervention model description
NTG vs Placebo
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
* All patients undergoing transradial catheterisation using proximal radial artery puncture technique
Exclusion criteria
* Blood pressure \<100 mmHg * Refuse to participate
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| The incidence of Moderate to severe radial artery spasm | During the index procedure | arm pain associated with catheter manipulation (RAS grade 2 to 4) |
Countries
Indonesia
Contacts
Primary ContactAgnes Intan, MD
Outcome results
None listed