Therapeutic Plasma Exchange
Conditions
Keywords
TPE, therapeutic plasma exchange, Side Effects
Brief summary
To assess the indications, tolerance and side effects of therapeutic plasma exchange (TPE) performed at a University Hospital over 8 years
Detailed description
Indications were recorded from the patients electronic chart. Side effects were identified from the review of TPE monitoring forms completed prospectively by the nurse who performed the TPE during the course of the procedure
Interventions
All TPEs were performed by the centrifugation technique using the Fresenius Kabi COMTEC machine
Sponsors
Rennes University Hospital
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Inclusion criteria
* All adult patients who underwent TPE in Rennes University Hospital 2011-2018
Exclusion criteria
* Absence of the monitoring sheet during the EP session * Refusal of patient participation after receipt of the information letter * Persons over the age of majority who are subject to legal protection (protection of justice, guardianship, guardianship)
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Frequency of side effects during Therapeutic plasma exchange | The inclusion day (retrospective study) | Occurrence of side effects, regardless of their severity during therapeutic plasma exchange sessions (From start of care by the nurse including the preparation for the insertion of peripheral or central venous access to disconnection from the device and removal of peripheral lines or closing the CVC),. Main side effects recorded are hypotension, tachycardia, shock, anaphylaxis, seizure, cardiac arrest, respiratory failure, skin rash, urticaria, catheter dysfunction, catheter related infection hypocalcemia, alkalosis. |
Countries
France
Outcome results
None listed