90-day Postoperative Surgical Site Infections, Superficial and Deep, Bacterial Transmission, Operating Room Exposure to S. Aureus, S.Aureus Transmission
Conditions
Keywords
Germicidal lights, S. aureus, Transmission, Operating room S. aureus exposure
Brief summary
Visible light at 405nm has been shown to be germicidal. The hypothesis is that use of this light (Indigo-Clean Lights) in operating rooms will reduce S. aureus transmission occurring within and between patients and reduce surgical site infections (SSIs). Investigators will evaluate a case-control study where patients undergoing surgery with the lights are matched with patients undergoing surgery without germicidal lights.
Detailed description
Operating room S. aureus exposure has been directly linked to postoperative infections and is therefore an important target for infection prevention. Visible light at 405nm has been shown to be germicidal. Investigators plan to install ambient, germicidal lighting (Indigo-Clean Lights) that uses this wavelength in 4 operating rooms. Patients will undergo surgery according to usual practice. Investigators will conduct a case-control study where patients undergoing surgery with the lights are matched with patients undergoing surgery without the germicidal lights. Patients will be matched by procedure then case duration then American Society of Anesthesiologists (ASA) physical status health classification. These patients will undergo infection surveillance. Infection surveillance will involve use of National Healthcare Safety Network (NHSN) checklists applied to patients who are positive for one or more of the initial screening criteria (elevated white blood cell count, fever (\>38.4 degrees Celsius), office note documentation of infection, positive culture (sputum, blood, urine, wound, other body fluid), or anti-infective order within the 90 postoperative day period.
Interventions
DEVICEGermicidal lighting
Germicidal ambient lighting
Sponsors
Kenall Manufacturing
University of Iowa
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
NONE
Intervention model description
Prospective Cohort Study
Eligibility
Sex/Gender
ALL
Age
18 Years to 120 Years
Healthy volunteers
Yes
Inclusion criteria
* Adult, at least 18 years old * Adult patients undergoing orthopedic, cardiothoracic, gyn/onc, and neuro surgery and general anesthesia according to usual care with peripheral and/or central venous access.
Exclusion criteria
* Pediatric (\<18 years old), * Incarcerated, and/or * Pregnant patients * Undergoing surgery and/or without peripheral or central venous access. * Undergoing surgery outside of the classifications above
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| S. aureus reservoir detection and/or epidemiologically-related transmission event in an OR observational unit. | Approximately 103 work days | OR reservoirs will be surveyed for S. aureus isolation and epidemiologically-relatedness assessed |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| 90-day postoperative SSIs, superficial and/or deep. | 1.6 years | surveillance of wound infections, superficial and deep |
| 90-day HAIs (combined incidence of SSIs, respiratory, blood stream, catheter-associated urinary tract, and C. Difficile infections). | 1.6 years | Surveillance of other healthcare-associated infections (HAIs) |
Countries
United States
Outcome results
None listed