Postoperative CRP Levels and Vaginal Cuff Hematoma

The Value of Postoperative CRP Levels to Predict Postoperative Vaginal Cuff Hematoma

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03879499

Enrollment

106

Registered

2019-03-18

Start date

2017-01-01

Completion date

2018-01-01

Last updated

2024-07-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative Hematoma

Keywords

cuff hematoma, CRP levels

Brief summary

After laparoscopic hysterectomy, authors aimed to determine cuff hematoma and a postoperative CRP value to help predict the other complications. A total of 136 patients who underwent total laparoscopic hysterectomy (TLH) were evaluated. CRP, White blood cell (WBC) and hemoglobin values (Hb) were measured on the 1st, 2nd and 7th days before and after the operation. Complications, pre-postoperative vaginal length and female sexual function were evaluated. Fourteen patients who developed cuff hematoma during postoperative follow-up were analyzed with the receiver operating characteristics (ROC) curve. ROC curves with the largest area under the curve for each inflammatory marker were compared in order to define the marker with higher diagnostic accuracy.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

FEMALE

Age

40 Years to 65 Years

Healthy volunteers

Inclusion criteria

women who underwent TLH operation with benign gynecological indications

Exclusion criteria

* Decided to switch to laparotomy during operation * postoperative complication due to relaparotomy * infection (including urinary system and lung infections) * Blood transfusion after TLH * with rheumatic diseases * length of hospital stay due to wound infection

Design outcomes

Primary

Measure	Time frame	Description
Relationship between CRP Levels and cuff hematoma; crp levels	1 week	The value of Postoperative CRP Levels to predict Postoperative Vaginal Cuff Hematoma ; To evaluate tissue trauma and surgical inflammatory responses, venous peripheral blood samples (C-reactive protein) were taken on the first, second and seventh day postoperatively. CRP values were measured under standardized conditions using turbidometry. CRP levels (mg / dl) were recorded.
Relationship between CRP Levels and cuff hematoma; cuff hematoma measurement	15 days	The patients were called to the outpatient clinic after the hysterectomy and evaluated by transvaginal ultrasonography (tvusg) for cuff hematoma.hematoma dimensions recorded in centimeters.

Outcome results