Acute Kidney Attack in Severe Traumatized Patients

Evaluation of the Incidence of Acute Kidney Attack by Dosing Nephrocheck® in Severe Traumatized Patients

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03877978

Acronym

NEPHROTRAUMA

Enrollment

196

Registered

2019-03-18

Start date

2019-05-16

Completion date

2021-12-02

Last updated

2022-05-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Kidney Injury

Brief summary

Acute Kidney Injury (AKI) is a common complication of severe traumatized patients. The diagnosis is often delayed. The Nephrocheck® test allows an earlier assessment of renal stress. The objective of our study is to determine the incidence of risk of AKI in severe traumatized patients within the first 24 hours after their admission to our trauma center. The risk of AKI is defined by a NephroCheck® test \>0.3

Interventions

BIOLOGICALNephrocheck test

Nephrocheck® measurement on urine sample at different timepoints.

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* age \>18 years * trauma patients with ISS ≥15 * patient admitted to the resuscitation bay of Edouard Herriot Hospital

Exclusion criteria

* anuric patient * opposition of the patient (or a trusted person) to participate * pregnant or lactating woman * age \<18 years

Design outcomes

Primary

Measure	Time frame	Description
Incidence of patients with Nephrocheck score > 0,3	Up to 24 hours after trauma	Incidence of severe traumatized patient at risk of AKI as defined by Nephrocheck test score \> 0,3 within the first 24 hours after admission

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026