Lyon Uveitis Study

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03877575

Acronym

LYS

Enrollment

750

Registered

2019-03-15

Start date

2016-01-01

Completion date

2025-01-01

Last updated

2024-04-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Uveitis

Brief summary

Uveitis or inflammation of the uveal tract results from a heterogeneous collection of disorders of varying etiologies and pathogenic mechanisms. Uveitis is relatively frequent in industrial countries with an estimation of 115 cases for 100 000 persons and is associated with a blindness risk of 10%. Causes of uveitis can be related to different etiologies (infectious, inflammatory or general inflammatory diseases). Therapeutic care is based on ophthalmologic and systemic diagnosis and treatment strategy depends on the severity of inflammation. The main objective of the Lyon uveitis study is to analyze the uveitis ophthalmologic etiology and diagnostic and therapeutic care of the patients. This study is proposed to all patients diagnosed for uveitis and referred to the Department of Internal Medicine of the Croix Rousse hospital, Lyon, france for etiologic diagnosis or treatment. Analysis of i) patients' characteristics, ii) the relevance of complementary exams to determine the uveitis etiology, iii) treatment used. This study will allow a better characterization of the disease on diagnosis practices and therapeutic care.

Interventions

OTHERNo specific intervention. Collection of clinical data

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Inclusion criteria

* Diagnosis of uveitis * First consultation in the Department of Internal Medicine at the Croix-Rousse hospital, Lyon, France

Exclusion criteria

Design outcomes

Primary

Measure	Time frame	Description
Clinical evolution (persistence or resolution) evaluated by gradation of SEN	At one year after diagnosis	Persistence of disease is characterized by persistence of intraocular inflammation evaluated by gradation of SEN. (reference: A Standardization Grading System for Scleritis . Ophthalmology 2011 Apr;118(4):768-71). SEN score ranges from 0 to 5 (resolution = score 0 and persistence = score \>0)

Countries

France

Contacts

Primary ContactPascal Sève, MD, PhD

pascal.seve@chu-lyon.fr+33-4 26 73 26 27

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026