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Comparison of Tidal Volume Between Pediatric Anaesthesia and Paediatric Intensive Care Patients

Comparison of Tidal Volume Between Pediatric Anaesthesia and Paediatric Intensive Care Patients: Retrospective Study

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT03877354
Acronym
TIVAC
Enrollment
1000
Registered
2019-03-15
Start date
2019-04-01
Completion date
2023-12-31
Last updated
2023-07-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Protective Ventilation

Keywords

ventilation, paediatric patient, mechanical ventilation

Brief summary

Paediatric anaesthesiology and paediatric intensive care unit data will be retrospectively screened for the data regarding mechanical ventilation. The primary aim will be the tidal volume setting and the secondary the level of positive end-expiration pressure (PEEP) according to the inspired oxygen fraction (FIO2), and the level of driving pressure.

Detailed description

Protective positive pressure ventilation (tidal volume ≤6 mL/kg) in adult patients in intensive care is currently considered as a standard procedure. It is associated with a reduction of morbidity and positive outcome. In paediatric patients there are available only limited information related to the size of the tidal volume and it is recommended to use the volume between 5 and 8 mL per kg for the whole spectrum of ages of pediatric patients. The aim of this retrospective observational study is to evaluate the tidal volumes used in clinical practice in pediatric patients during general anesthesia and compared it to the tidal volumes used in paediatric critical care. Data will be harvested from the anaesthesiology records and from the paediatric intensive care unit charts. The tidal volume will calculated per kg of actual weight.

Interventions

OTHERData from anaesthesia records for ventilation setting screening

Data from anaesthesia records will be retrospectively screened for the ventilation settings

OTHERData from intensive care records for ventilation setting screening

Data from paediatric intensive care charts will be retrospectively screened for the ventilation settings

Sponsors

Brno University Hospital
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
No minimum to 19 Years
Healthy volunteers
No

Inclusion criteria

* Paediatric patients on mechanical ventilation in anaesthesia department * Paediatric patients on mechanical ventilation in intensive care department * In selected study period between 1.1.2018 - 31.1.2019

Exclusion criteria

* Age outside selected limits * Insufficient data

Design outcomes

Primary

MeasureTime frameDescription
Tidal volumeIntraoperative periodTidal volume will be evaluated in the paediatric patients in anaesthesia and in intensive care unit

Secondary

MeasureTime frameDescription
Positive end-expiratory pressure settings according to the inspiration fraction of oxygenIntraoperative periodPositive end-expiratory pressure will be evaluated in the paediatric patients in anaesthesia and in intensive care unit
Driving pressureIntraoperative periodDriving pressure will be calculated from peak pressure minus PEEP in patients on mechanical ventilation in anaesthesia and in intensive care unit

Countries

Czechia

Contacts

Primary ContactPetr Stourac, assoc.Prof.MD.Ph.D
stourac.petr@fnbrno.cz532234404
Backup ContactJozef Klucka, MD
Klucka.jozef@fnbrno.cz532234696

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026