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Sagittal Parameters After Mono Segmental Lumber Fusion: Interbody Versus Postrolateral Fusion

Sagittal Parameters After Mono Segmental Lumber Fusion: Interbody Versus Postrolateral Fusion

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT03877341
Enrollment
42
Registered
2019-03-15
Start date
2019-04-01
Completion date
2023-03-01
Last updated
2023-09-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lumbar Spine Fusion

Brief summary

To compare postoperative radiographic sagittal parameters after monosegmental lumbar fusion: posterior lumbar interbody fusion versus postrolateral fusion in treatment of lumbar spine instability

Detailed description

The term spondylolisthesis refers to slipping of a vertebra relative to an adjacent vertebra,and there are two mean types degenerative and lytic : Degenerative spondylolisthesis is secondary to osteoarthritis leading to facet incompetence and disc degeneration.This condition allows anterior translation of one vertebra on another. Spondylolysis is the break in the pars interarticularis and is the precursor of lytic spondylolisthesis which associated with a pars fracture When nonoperative care fails and surgery is being considered, the type of fusion should be tailored to the specific pathology being treated.So there are different operations to correct this instability like postrolateral fusion (PLF) and posterior lumber interbody fusion (PLIF) PLF decreases segmental motion in the posterior column, which presumably reduces facet joint pain.Theoretical advantages of PLIF include decompression of exiting nerve roots by distraction of the collapsed disc space, achievement of optimal fusion in relation to the load-bearing capacity of the vertebral bodies and possibly attainment of a better fusion rate

Interventions

Instrumented posterolateral fusion is a spinal surgery that combines bone graft fusion with the use of hardware like screws and rods to stabilize the spine, correct alignment, and promote successful fusion. It's used for various spinal conditions.

Posterior lumbar interbody fusion (PLIF) is a spinal surgery that involves removing problematic discs, inserting bone graft material, and sometimes a spacer, to promote fusion and stabilize the spine.

Sponsors

Assiut University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Adult patient older of 18 years old. * Patients with lytic spondylolisthesis * Low grade spondylolisthsis 1,2

Exclusion criteria

* Traumatic spondylolysis * Previous spine surgery. * Patient younger 18 years old * High grade spondylolisthsis 3,4,5 - multiple levels spondylolithises

Design outcomes

Primary

MeasureTime frameDescription
Spino sacral angle6month post opWhich is the angle fromed between the line from front side of t1 to the middle of sacrum and the line passing through the sacral plateau

Secondary

MeasureTime frameDescription
T1 pelvic anglePre op. Post op immediately. 6month post opThe angle between the line from centroid of t1 to the femoral head axis and the line from femoral head axis to middle of the s1 end plate
Pelvic incidencePre op. Post op immediately. 6month post opIs the angle between the line perpendicular to the s1 end plate from the midpoint of the end plate and the connecting line from the midpoint of the s1 end plate to center of the femoral head
Pelvic tiltPre op. Post op immediately. 6month post opIs the angle between the connecting line from the midpoint of the s1 end plate to the center of the femoral head and the vertical line
Sacral slopePre op. Post op immediately. 6month post opIs the angle between the tangent and the horizontal line of s1 end plate
Lumbar lordosisPre op. Post op immediately. 6month post opIs the junction of the thoracic kyphosis to the s1 end plate

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026