Clinical Effectiveness of Erector Spinae Plane Block in Peri-operative Analgesia for Laparoscopic Nephrectomy/Nephron Sparing Surgery (NSS)/Hynes-Anderson Procedures.

Clinical Effectiveness of Erector Spinae Plane Block in Peri-operative Analgesia for Laparoscopic Kidney Procedures

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT03874091

Enrollment

Registered

2019-03-14

Start date

2019-01-15

Completion date

2021-10-01

Last updated

2021-11-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Erector Spinae Plane Block

Keywords

Erector Spinae Plane block, ESP block, Laparoscopic Nephrectomy

Brief summary

62 patients age of 20 to 85, (ASA) physical status I-III undergoing laparoscopic nephrectomy/NSS/Hynes Anderson procedures in 1st Department of Anesthesiology in Warsaw will be enrolled in the study. Patients will be randomised into 2 groups - patients from the first group will undergo General Anaesthesia (GA) with intravenous analgesia peri-operatively, patients from the second group will receive GA plus the Erector Spinae Plane Block (ESP block) bilaterally performed under ultrasound guidance with catheter left on the side of surgery. Ultrasound transducer will be placed in a longitudinal orientation 3 cm lateral to the Th7 spinous process. Three muscles will be identified superficial to the hyperechogenic transverse process shadow as follows: trapezius, rhomboid major, and erector spinae. An 8-cm 18-gauge block needle will be inserted in a cephalad-to-caudad direction until the tip gets in the interfascial plane between rhomboid major and erector spinae muscles, as evidenced by visualization of local anesthetic spreading in a linear pattern between erector spinae and the bony acoustic shadows of the transverse processes. . Patients in this group will be anesthetized with 20ml 0,25% bupivacaine + Adrenaline 1:200 000 for each side. ESP block will be performed at the level of Th7-8 after proper positioning he patient in the sitting position before GA then standard technique of catheter application will be applied. After the surgery the elastomeric pump will be attached to the catheter with 0,125% bupivacaine with Adrenaline 1:200 000. Anaesthesia will be standardised In the both groups.

Interventions

PROCEDUREbilateral ESP block with 0,25% Bupivacaine+ Adrenaline

Regional anaesthesia technique performed under ultrasound guidance before surgery

PROCEDUREESP block continuous infusion with 0,125% Bupivacaine+Adrenaline

Continous infusion of Local Anaesthetic (LA) given postoperatively via the catheter.

DRUGMorphine PCA pump

Morphine given postoperatively.

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

20 Years to 85 Years

Healthy volunteers

Inclusion criteria

* pts undergoing laparoscopic nephrectomy/NSS/Hynes Anderson procedures in 1st Department of Anaesthesiology in Warsaw * pts consented for the study prior to surgery * ASA 1-3

Exclusion criteria

* Pts without consent for trial * Pts ASA 4-5 * Coagulation abnormalities * Allergy to local anesthetics * Skin lesions in the place of needle insertion

Design outcomes

Primary

Measure	Time frame	Description
Postoperative Morphine Requirements	24 hours post surgery	Patient Controlled Analgesia (PCA) morphine consumption in both groups will be recorded.

Secondary

Measure	Time frame	Description
Intraoperative Fentanyl Requirements	Time of surgery.	Fentanyl consumption in both groups will be recorded

Other

Measure	Time frame	Description
Postoperative Nausea and Vomiting (PONV)	24 hours post surgery.	Postoperative nausea and vomiting will be recorded if occurred

Countries

Poland

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026