Atopic Dermatitis, Gas Sensor, Healthy Adults, Sweat Sensor, Wearables
Conditions
Brief summary
Pilot study of a wearable gas and sweat skin sensor
Detailed description
The objective of this study is exploratory and deploys two wearable sweat and gas sensors which detect the composition of sweat proteins and volatile gases emitted from the skin in healthy subjects and patients with atopic dermatitis.
Interventions
DEVICEGas sensor
The gas sensor is an airtight gas capsule attached with a floating solid phase microextraction (SPME) tube. SPME uses a fiber coated with a nontoxic liquid (polymer), and a nontoxic solid (sorbent). The fiber coating extracts the compounds from the gas being released from the skin. Only the glass sample is in contact with the skin.
DEVICESweat Sensor
The sweat sensor is a soft, flexible device that rests on the skin and collects secreted sweat through capillary action. The device is held in place by medical-grade acrylic adhesive film.
Sponsors
Northwestern University
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* Age ≥18 years old * Subjects willing and able to comply with requirements of the protocol * Healthy adults or subjects with atopic dermatitis
Exclusion criteria
* Age \<18 years old * Subjects unwilling and able to comply with requirements of the protocol * History of skin allergy to medical adhesive tape * History of heat stroke, heat related or exercise related * Non-English speaking subjects
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Evaluation of gas exudates | 20 minutes | Evaluation of protein contents from gas exudates from the skin |
| Evaluation of sweat proteins | 20 minutes | Evaluation of protein contents from sweat from the skin |
Countries
United States
Outcome results
None listed