To Compare Intravenous and Oral Hydration of the Prevention for CIN in Elderly Patients Undergoing Intravenous CECT

To Compare Intravenous and Oral Hydration of the Prevention for Contrast-induced Nephropathy in Elderly Patients Undergoing Intravenous Contrast-enhanced Computed Tomography： A Multi-center Randomized Control Trail

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT03872739

Acronym

CINOECT

Enrollment

1368

Registered

2019-03-13

Start date

2016-10-08

Completion date

2021-10-31

Last updated

2019-03-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

CIN

Keywords

CIN, Hydration, enhanced computed tomography

Brief summary

To Compare Intravenous and Oral Hydration of the Prevention for Contrast-induced Nephropathy in Elderly Patients Undergoing Intravenous Contrast-enhanced Computed Tomography.

Detailed description

The prospective multicenter randomized controlled clinical research discusses the comparison of oral and intravenous hydration for prevention of contrast-induced nephropathy in elderly patients with enhanced computed tomography, establishing a simple hydration proposal.

Interventions

PROCEDUREenhanced computed tomography

undergoing enhanced computed tomography

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

65 Years to No maximum

Healthy volunteers

Inclusion criteria

* Age\>21 * informed consent * Undergoing Intravenous Contrast-enhanced Computed Tomography

Exclusion criteria

* CT enhancement was not performed; * Dialysis treatment of patients with end-stage renal failure or heart, kidney transplantation; * Exposure to radioactive contrast medium within 48 hours prior to or within 72 hours of examination; * Acute decompensated heart failure; * Allergic to radioactive contrast agent; * Be subjected to life - threatening trauma; * Severe infection; * Surgery was performed within 2 days of CT examination. * Combined with multiple myeloma, urinary obstruction, aortic dissection * Can cause acute kidney injury disease; * Use of aminoglycosides and other nephrotoxic drugs 2 weeks before.

Design outcomes

Primary

Measure	Time frame	Description
CIN	72hours	Compared with before examination, the increase of serum creatinine conforms to the diagnostic criteria of contrast induced nephropathy.

Countries

China

Contacts

Primary ContactDanqing Yu, Doctor

gdydq100@126.com13631349257

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026