Flash Glucose Measurement in Patients on Total Parenteral Nutrition

What Happens to Frequently Measured Glucose Measures in Patients, Both With and Without Diabetes, Who Are Receiving Total Parenteral Nutrition (TPN).

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT03871660

Enrollment

Registered

2019-03-12

Start date

2019-03-01

Completion date

2019-10-31

Last updated

2019-05-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diabetes Mellitus

Keywords

Total Parenteral Nutrition

Brief summary

IV nutrition is a means of providing all the nutritional requirements of people who have severe bowel disease. At least 10% of people on longer term IV nutrition also have diabetes and IV nutrition includes delivering glucose directly to large veins. Unsurprisingly this causes elevated blood glucose levels, particularly in people with diabetes. This can make treatment of hyperglycaemia more challenging. As a result this study aims to use a flash glucose monitoring device, the FreeStyle Libre pro, to investigate what happens to glucose levels in patients receiving IV nutrition. We will look at this trend in 5 patients with diabetes and 5 patients without diabetes receiving IV nutrition.

Interventions

DEVICEFreeStyle Libre Pro

Flash glucose monitoring device. Measures patients interstitial glucose levels continuously.

Study design

Allocation

NON_RANDOMIZED

Intervention model

SINGLE_GROUP

Primary purpose

BASIC_SCIENCE

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to 80 Years

Healthy volunteers

Yes

Inclusion criteria

* Participants receiving TPN in Leeds with or without diabetes

Exclusion criteria

* Patients not receiving TPN * Patients who do not speak English * Patients who are unable to give consent

Design outcomes

Primary

Measure	Time frame	Description
Hyperglycaemia	14 days	Measurements of hyperglycaemia through interstitial glucose levels in patients on a TPN regime

Countries

United Kingdom

Contacts

Primary ContactMichael W Mansfield, BM BCh, BA (hons)

michael.mansfield@nhs.net01132066963

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026