Gastroesophageal Reflux Disease, Globus Pharyngeus
Conditions
Keywords
High resolution manometry, globus pharyngeus, gastroesophageal reflux disease, manual cervical traction, trunk stabilization maneuver
Brief summary
The aim of this study is to test the influence of manual cervical traction and chest stabilization maneuvers on pressures in upper and lower esophageal sphincters.
Detailed description
High Resolution Manometry (HRM) will be used to measure pressure changes in upper esophageal sphincter (UES) and lower esophageal sphincter (LES) during manual cervical traction and trunk stabilization maneuvers. 50-55 gastroesophageal reflux disease (GERD) subjects will participate in the study. UES and pressures will first be measured in relaxed supine position then, during manual cervical traction and finally, the subjects will undergo manual positioning of the trunk into neutral position and LES and UES pressures will be measured again.
Interventions
Manual Cervical Traction, Trunk Stabilization Maneuver
Sponsors
Study design
Eligibility
Inclusion criteria
* Gastroesophageal reflux disease
Exclusion criteria
* Previous gastro- esophageal surgery * Concomitant other chronic disease that would affect esophageal motility * Esophageal structural pathology * Massive hiatus hernia
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Pressure in upper and lower esophageal sphincter | up to 6 months | Pressure in upper and lower esophageal sphincter at rest, during cervical manual traction, and during trunk stabilization maneuver |
Countries
Czechia