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Comparing Site-selection Strategies

Comparing Site-selection Strategies for Improving Speech Recognition Outcomes

Status
Withdrawn
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT03870217
Enrollment
0
Registered
2019-03-12
Start date
2020-08-01
Completion date
2023-04-04
Last updated
2024-06-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Deafness

Brief summary

Several studies in the past have tried to deactivate electrodes that are less optimal to improve speech recognition outcomes. The study aims to compare the measures based on which the deactivation was performed. The investigators aim to first examine if the measures are strongly correlated each other, and then compare the deactivation effects across measures. These measures are mainly behavioral including electrode discrimination, amplitude modulation detection thresholds, low-rate and focused detection thresholds and electrode-modiolus distance. The endpoint of the study is speech recognition performance post deactivation.

Interventions

BEHAVIORALSite selection

Turning off electrodes on the electrode array based on imaging and psychophysical measures

Sponsors

East Carolina University
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
15 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

* Native speakers of English * Cochlear Nucleus cochlear implant users or Advanced Bionics users * Postlingually deafened * Has had device experience for at least one year * Can be child or adult at the time of enrollment

Exclusion criteria

* None

Design outcomes

Primary

MeasureTime frameDescription
Speech recognition with deactivation12 months post award notice and will take up to 3.5 years to completeElectrodes will be evaluated based on (1) pitch discrimination (2) focused thresholds (3) amplitude modulation detection thresholds and (4) distances from the modious. Electrodes will be deactivated based on each of these measures and speech recognition will be evaluated to assess the effect of deactivation. The benefit of deactivation (speech recognition after deactivation minus before deactivation) will be derived for each measure. The measure that produces the greatest benefit will be identified.

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026