Changes in Brain Tissue Pulsatility With Musical Stimuli

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03867422

Acronym

M-PULSE

Enrollment

Registered

2019-03-08

Start date

2019-04-02

Completion date

2019-04-26

Last updated

2019-08-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy

Brief summary

Music Perception is well known to elicit emotions and neuronal activations. Changes in the cerebrovascular physiology have also been found in emotional tasks but only few studies have investigated markers of cerebrovascular physiology in a music task and no study has used the Ultrasound method of Tissue Pulsatility Imaging (TPI) in a music task. The use of TPI to measure reactivity of Brain Tissue Pulsatility Imaging (BTP) could further elucidate the cerebral basis of music perception.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 45 Years

Inclusion criteria

* more or equal 18 years-old and less or equal 45 years-old * no known hearing problem

Exclusion criteria

* professional musician * history of neurologic, psychiatric or cadiologic disease * treatment which could impact parameters of brain tissue pulsatility and peripheral nervous system * opposition to use the data

Design outcomes

Primary

Measure	Time frame	Description
amplitude of variations in brain tissue pulsatility	Baseline	in micrometers

Secondary

Measure	Time frame	Description
heart rate	Baseline	beat by minute
breathing rate	Baseline	Frequency
skin conductance	Baseline	in milliVolt
score of barcelona music reward questionnary (BMQR)	Baseline	BMQR: Barcellona Music Reward Questionnaire for the evaluation of musical anhedonia; * Only the total score of musical reward will be reported; for total score, minimum value is 20, maximum value is 100. Values under 40 represent low values in the overall score; values above 60 indicate high values in the overall score; * High global score (\>60) represents a better outcome; low global score (\<40) represents a worse outcome, notably an impairment in music reward processing; * The overall score is computed by adding raw scores of the items (except for items 2 and 5, which need to be reversed).

Countries

France

Outcome results