Dental Calculus, Infection
Conditions
Keywords
Infection, genomic, dental calculus
Brief summary
We are studying the possibility of using dental calculus as a reservoir for the genes of an infectious agent that has infected the patient in previous months; as it is done to highlight climate change in ice samples.
Detailed description
From a sample of people who have had a microbiologically well-documented infection, we will study the possibility after genomic amplification to find, three to 12 months after genetic sequences of the infectious agent in the dental calculus of the person. The people will be recruited according to a large panel of infectious agent (gram + and gram bacterium, mycobacteria, parasite, fungus, DNA, RNA or retrovirus) and, of course, the presence of dental calculus.
Interventions
None listed
Sponsors
University Hospital, Brest
Study design
Observational model
CASE_ONLY
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Inclusion criteria
* three months before, having been infected with a documented pathogen * this infection must have been clinically obvious * the patient must have dental calculus
Exclusion criteria
* to be under 18 years old * to be incapable to consenting * a tartar removal since the infection
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| successful detection of pathogen | 3 to 12 months | detection of infectious agent |
Countries
France
Contacts
Primary ContactLuc de Saint-Martin, MD, PhD
Backup ContactSophie Vallet, MD, PhD
Outcome results
None listed