Postoperative Analgesia
Conditions
Keywords
TAP block, inguinal hernia
Brief summary
To compare the postoperative analgesic effect of two doses of dexamethasone added to bupivacaine in ultrasound-guided TAP block for inguinal hernia repair.
Detailed description
The transverses abdominis plane block (TAP block) is a regional anesthesia technique that provides analgesia following abdominal surgery . The TAP block significantly reduces pain after open inguinal hernia repair, regardless of whether it is used as a primary anesthesia technique or as a complement to general anesthesia, spinal or local anesthesia . The investigators designed this study to compare the postoperative analgesic effect of two doses of dexamethasone( 4 mg and 8 mg ) added to bupivacaine in ultrasound-guided TAP block for inguinal hernia repair.
Interventions
DRUGDexamethasone
After the surgery, dexamethasone added to 1mg/kg of 0.5% bupivacaine in the TAP block.
DRUGBupivacaine
After the surgery,1mg/kg of 0.5% bupivacaine in the TAP block.
Sponsors
Assiut University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)
Masking description
A blinded physician prepared the study medications in color coded syringes.
Intervention model description
60 patients will be divided into two groups according to the dose of dexamethasone added to bupivacaine in the TAP block, I - group ( Group D4 ) 4mg of dexamethasone will be added II - group ( Group D8 ) 8mg of dexamethasone will be added. III-group(control) bupivacaine alone
Eligibility
Sex/Gender
MALE
Age
18 Years to 60 Years
Healthy volunteers
No
Inclusion criteria
* Patients' age from 18 to 60 years old, * physical status ASA I-II (by the American Society of Anesthesiologists), * Elective unilateral open inguinal hernia repair, * Under spinal anesthesia
Exclusion criteria
* age \< 18 or \> 60, * American society of anesthesiologist (ASA)class III-IV, * known allergy to amino amide local anesthetics, * skin infection and diseases at site of injection. * coagulation disorders, * patients with body mass index (BMI) \> 35 kg/m2, * scrotal hernias,
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| time of the first analgesic request | in the first postoperative 24 hours | time of the first analgesic request in the first postoperative 24 hours ,patients will receive analgesia if visual analog scale (VAS) score more than 3 |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| change in visual analog scale (VAS) | 2nd, 4th, 8th, 16th, and 24th postoperative hours. | measuring the change in visual analog scale VAS (0: no pain to 10: worst imaginable pain), to evaluate postoperative analgesia |
Countries
Egypt
Outcome results
None listed