Chronic Obstructive Pulmonary Disease
Conditions
Brief summary
The aim of the study is to investigate the efficacy of upper limb exercise training in Chronic Obstructive Pulmonary Disease (COPD) patients. For the purpose of the study, a controlled trial will be conducted within Respiratory Clinic of Nicosia General Hospital. The sample will be divided in two groups. The intervention group will participate in a pulmonary rehabilitation program which includes upper and lower extremities exercises, with addition of arm ergometer. The second group (control group) will participate in the same program but without arm ergometer training. The study's hypothesis is that the intervention group will improve the outcome measures significantly better than the control group.
Interventions
OTHERArm Endurance Exercise Training
Pulmonary Rehabilitation Program including Upper Limb Endurance Exercise Training with arm cycle ergometer
OTHERControl
Pulmonary Rehabilitation Program without Upper Limb Endurance Exercise Training
Sponsors
Nicosia General Hospital
European University Cyprus
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
DOUBLE (Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Diagnosis of COPD confirmed by clinical examination and a pulmonary function test * Stable clinical condition (without recent respiratory system infections or any exacerbation of the disease) * Patients must be willing to re evaluate at the end of the study * Patients must be willing to give written consent for their participation in the study
Exclusion criteria
* Age \< 18 years old * Unstable cardiac disease * Musculoskeletal and neurological diseases that could affect exercise performance or preclude exercise * Patients of COPD final stage or other serious disease final stage * Significant cognitive or psychiatric impairment that would lead to an inability to follow simple commands in a group setting
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Upper Limb Muscle Strength, triceps | Before Intervention | Assess triceps via hand-held dynamometer Micro FET2 |
| Upper Limb Muscle Strength, hand-grip | Before Intervention | Assess via jamar hand dynamometer |
| Upper Limb Muscle Strength, biceps brachii | Before Intervention | Assess biceps brachii via hand-held dynamometer Micro FET2 |
| Dyspnea, modified Borg Scale | Before Intervention | Assess via modified Borg Scale 0 - 10, 0 = no dyspnea, 10 = maximal dyspnea |
| Dyspnea, mMRC Scale | Before Intervention | Assess via modified Medical Research Council Dyspnea Scale 0 - 4, 0 = breathless only with strenuous exercise, 4 = too breathless to leave the house or breathless when dressing |
| Fatigue | Before Intervention | Assess via modified Borg Scale (0 - 10), 0 = no fatigue, 10 = maximal fatigue |
| Health-related Quality of Life, SGRQ | Before Intervention | Assess via Saint George Respiratory Questionnaire, A total score incorporates scores from each component of the SGRQ which ranges from 1 to 100, where 0 indicates best health and 100 indicates worst health |
| Health-related Quality of Life, CAT | Before Intervention | Assess via COPD Assessment Test (CAT), Range of CAT scores from 0-40. Higher scores denote a more severe impact of COPD on a patient's life. |
| Activities of Daily Living with Upper Limbs | Before Intervention | Assess via total time need to perform 3 daily activities: (i) simulating of window cleaning, (ii) dry 10 dishes and putting them on a shelf above shoulder level and (iii) putting three packages, each weighing 1000 g, on a shelf above shoulder level |
Countries
Cyprus
Contacts
Primary ContactChristos Karagiannis
Outcome results
None listed