Post Thoracic Surgery
Conditions
Brief summary
While thoracic epidural could control incisional pain after thoracotomy, an excruciating ipsilateral shoulder pain happens post thoracotomy and could affect up to 85% of thoracotomy patients. It is often difficult to manage and relatively resistant to opioids. The investigators postulate that in the presence of a functioning thoracic epidural, intrapleural bupivacaine administered through the chest tube could be effective in reducing post thoracotomy ipsilateral shoulder pain.
Interventions
See previous description
DRUGNormal saline
See previous descreption
Sponsors
McGill University Health Centre/Research Institute of the McGill University Health Centre
Study design
Allocation
RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Outcomes Assessor)
Masking description
Blinded drug preparation
Intervention model description
RCT with one active group and a control (placebo) group
Eligibility
Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
Yes
Inclusion criteria
* Male and Female, between 18 and 80 years, ASA 1-3, Scheduled for open thoracotomy
Exclusion criteria
* ASA \>3, morbid obesity BMI\>40, Previous cardiac or ipsilateral thoracic surgery, Renal or hepatic failure, anemia, allergy to local anesthetics, contraindications to receive regional anesthesia, patient refusal, reiteration due to complication
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in VAS scores | from 0 hour to 24 hour | ISP visual analogue scale scores before intrapleural block and at 30 min, 4 hours and 24 hours |
Secondary
| Measure | Time frame |
|---|---|
| Forced Vital Capacity | from 0 hour to 48 hour |
| Total epidural infusion | from 0 hour to 48 hour |
| Co-analgesia consumption | from 0 hour to 48 hour |
Countries
Canada
Outcome results
None listed