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Effects of Physical Activity on Weight Loss and Weight Maintenance in Obese Adults - Three Year Follow-up Study

Effects of Physical Activity on Weight Loss and Weight Maintenance in Obese Adults - Three Year Follow-up Study

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT03861754
Acronym
LILA
Enrollment
120
Registered
2019-03-04
Start date
2004-01-28
Completion date
2010-05-31
Last updated
2019-03-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy Obesity, Metabolically, Obesity, Physical Activity, Weight Loss

Keywords

Obesity, Weight loss, Weight maintenance, Physical activity, Fitness

Brief summary

Objective To study if exercise added to weight loss treatment at the beginning of the weight loss intervention or at 6 months could sustain the weight loss achieved or give extra boost for weight reduction. Design 36-month, 4-group parallel, randomized trial. Setting Oulu, Finland. Participants 120 obese adults (body mass index ≥ 30). Intervention Participants were randomly assigned to behavioural modification (iBM) (n = 30), behavioural modification + exercise from 0 to 3 months (CWT1) (n = 30), behavioural modification + exercise from 6 to 9 months (CWT2) (n = 30), and a control group (CON) (n = 30). Questionnaires and measurements were performed at baseline, 3,9,4 and 36 months. The intervention consisted of an intensified weight loss period (1-12 months) followed by a weight maintenance period (13-36 months). Intensified behavioural modification included 14 individual face to face meetings, eleven times with a personal therapist (qualified nurse) and three times with a nutritionist. Weight maintenance period included six individual meetings with personal therapist. Twelve weeks supervised exercise was offered three times a week, 40 minutes at a time. In the CWT1 group supervised exercise was offered at months 1-3 and in the CWT2 group at months 4-6. Measurements Body weight (primary outcome) and waist circumference (secondary outcome)

Interventions

BEHAVIORALLifestyle modification

Sponsors

Oulu Deaconess Institute Foundation sr
CollaboratorUNKNOWN
Oulu University Hospital
CollaboratorOTHER
University of Oulu
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to 64 Years
Healthy volunteers
No

Inclusion criteria

* Body mass Index \> 30 * Age 18-64

Exclusion criteria

* Pregnancy * Health reasons preventing exercise and exercise test * Medication preventing exercise and exercise test * Previously diagnosed diabetes

Design outcomes

Primary

MeasureTime frameDescription
Weight changeChange from baseline weight at 36 monthsKilograms

Secondary

MeasureTime frameDescription
Waist circumference changeChange from baseline waist circumference at 36 monthsCm

Countries

Finland

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026