Epileptic Seizure
Conditions
Keywords
Status epilepticus, Electroencephalogram, Intensive Care Unit
Brief summary
This retrospective observational cohort study is to assess and analyze clinical, electroencephalographic, laboratory, comorbidity, and treatment characteristics of Intensive care unit (ICU)-patients with epileptic seizures and to subsequently compare their characteristics with ICU-patients with status epilepticus (SE).
Detailed description
The aim of this retrospective observational cohort study is to get further insight into adult patients with epileptic seizures in ICUs in an academic tertiary medical care center regarding frequency, clinical and electroencephalogram (EEG) characteristics, treatment, course and outcome. This data could help understanding the epidemiology (including risk factors, influence of EEG), and to guide management and improve outcomes of affected patients.
Interventions
Patient data will be collected using the in-house digital patient record systems and the local digital electroencephalogram (EEG)-database
Sponsors
University Hospital, Basel, Switzerland
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* admitted to the ICU at the University Hospital Basel * suffered from one or more epileptic seizures (detected clinically and/or by EEG) during their ICU-stay
Exclusion criteria
* patients with epileptic seizures transforming into Status epilepticus (SE)
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Frequency of epileptic seizures | between 01.01.2005 and 19.12.2018 | Frequency of all epileptic seizures in the ICU |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Number of epileptic seizures captured by EEG | between 01.01.2005 and 19.12.2018 | Number of epileptic seizures captured by EEG without overt clinical seizure presentation in the ICU |
| Number of epileptic seizures diagnosed on the basis of clinical symptoms alone | between 01.01.2005 and 19.12.2018 | Number of epileptic seizures diagnosed on the basis of clinical symptoms alone in the ICU |
| Length of epileptic seizure (time) | between 01.01.2005 and 19.12.2018 | Duration of epileptic seizure |
| Semiological feature of epileptic seizure (i.e. seizure types) | between 01.01.2005 and 19.12.2018 | Semiological feature of epileptic seizure (i.e. seizure types) emerging in ICU-patients |
Countries
Switzerland
Outcome results
None listed