Aging, Cognitive Decline, Cognitive Impairment, Motor Coordination or Function
Conditions
Keywords
cognition, mobility, cognitive reserve, EEG/ERP
Brief summary
Within this project the investigators tested the effectiveness of 2-month of computerized cognitive training (CCT) on CogniFit online platform on 77 older adults, which were randomly divided into intervention and control group. The investigators tested close (battery of cognitive functions) and far transfer (postural and mobility control, EEG, blood samples) of the CCT. Additionally, the investigators were interested into seeing a long-lasting effect, therefore participants were brought back to the laboratory 1 year post CCT.
Interventions
OTHERComputerized cognitive training
Intervention used CogniFit platform with Personalized brain training sub-option
Sponsors
University of Primorska
Albert Einstein College of Medicine
Vrije Universiteit Brussel
Science and Research Centre Koper
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Subject)
Masking description
A single-blind randomized controlled trial
Intervention model description
Participants in the intervention group followed a computerized cognitive training program for 2-months, 3x/week, 40min/session
Eligibility
Sex/Gender
ALL
Age
60 Years to 90 Years
Healthy volunteers
Yes
Inclusion criteria
* active and healthy older adults with no major health issues * members of the Center for Daily Activity Koper (Slovenia) * had normal or corrected-to-normal vision; * reported no history of cardiovascular, neurological, or psychiatric conditions
Exclusion criteria
* younger than 60 * smoking; regular alcohol consumption; * acute or chronic skeletal, neuromuscular, metabolic and cardiovascular disease condition;
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in gait speed | up to 8 weeks | The primary outcome is change in gait speed during single- and dual-task conditions from baseline to post-intervention. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Executive control (Trail-Making Task Forms A and B) | up to 8 weeks | Secondary outcome is change in executive control, measured with TMT A and B tests |
| Sensorimotor integration measured with EEG/ERP methodology | up to 8 weeks | Secondary outcome is change ERP components P1, N1, P2 and P3 (amplitudes and latencies) |
| Brain-derived neurotrophic factor (BDNF) extracted from peripheral blood sampling | up to 8 weeks | Secondary outcome is change in plasma BDNF plasma extraction evaluated in pg/mL |
Countries
Slovenia
Outcome results
None listed