Study of the Loss of AV Synchrony at Maximum Exercise

SLAVSME - Study of the Loss of AV Synchrony at Maximum Exercise

Status

Terminated

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03859167

Acronym

SLAVSME

Enrollment

Registered

2019-03-01

Start date

2019-09-10

Completion date

2023-04-10

Last updated

2023-04-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Exercise, Pacemaker, Blood Pressure

Brief summary

Investigators will identify a group of patients with complete heart block and a dual chamber pacemaker who will be expected to be able to exercise on a treadmill. Investigators will utilize symptom logs, cuff and continuous blood pressure monitoring. It is planned to study the symptomatic impact of loss of AV synchrony at significant levels of exercise.

Interventions

OTHERStress Test

Participants will reach maximum exercise on a treadmill and results will be collected and recorded.

Study design

Observational model

CASE_ONLY

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 60 Years

Inclusion criteria

* Complete AV Block * Age less than 60 * Easily programmable dual chamber pacemaker

Exclusion criteria

* Age \> 60 * Significant Heart Failure * Significant angina * History of claudication * Significant orthopedic issues * Evidence of sinus node dysfunction * Taking beta blockers or non-dihydropyridine calcium channel blockers

Design outcomes

Primary

Measure	Time frame
The number of participants with Loss of AV synchrony at maximum exercise	Baseline to end of stress test approximately 60 minutes.

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026