Endothelial Cell Loss, Corneal
Conditions
Brief summary
Cataract surgery is one of the most frequently performed surgical procedures worldwide. Since the introduction of phacoemulsification to remove the cataractous lens, risk and complication rates of cataract surgery decreased significantly. The phacoemulsification technique utilizes a high-intensity ultrasound energy for the fragmentation and emulsification of the lens. One of the main complications during phacoemulsification, is damaging of the endothelium due to contact with lens fragments of the nucleus following turbulent flow of irrigating solution, resulting in corneal damage, inflammation of the endothelium and corneal edema. In this study we want to evaluate the effect of the anterior capsule, gained by capsular rhexis, as a corneal shield during phacoemulsification on the corneal endothelium.
Interventions
PROCEDURERhexis protection shield
In the study group the anterior capsule will be used as a protection shield during pacoemulsifikation and removed after the phacoemulsifikation
Sponsors
Prim. Prof. Dr. Oliver Findl, MBA
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
21 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Cataract * Age 21 and older * Written informed consent prior to surgery * Moderate to severe nuclear or mixed cataract
Exclusion criteria
* Corneal pathologies * Pregnancy * Patients with an increased surgical risk (i.e. patients with pseudoexfoliation syndrome, patients with the potential risk of intra-operative floppy iris syndrome)
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| endothelium cell loss | 1 year | Comparison of the lost endothelium cells in both groups |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| central corneal thickness | 1 year | Comparison of corneal thickness between both groups |
Outcome results
None listed