Skip to content

Evaluation of the Effect on Optic Nerve Sheath Diameter in Patients Undergoing Cesarean Section

Evaluation of the Effect of Epidural Anesthesia on Optic Nerve Sheath Diameter in Patients Undergoing Cesarean Section

Status
UNKNOWN
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT03853889
Acronym
EONSDCS
Enrollment
35
Registered
2019-02-26
Start date
2019-06-28
Completion date
2019-12-17
Last updated
2019-07-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Intracranial Pressure

Keywords

optic nerve sheath pressure, noninvasive intracranial pressure measurement, epidural anesthesia, cesarean

Brief summary

Depending on the physiology of pregnancy, the risk of increased aspiration, difficult airway, increased oxygen consumption and reduced functional residual capacity, breathing problems make general anesthesia application risky. In obstetric operations, neuraxial anesthesia is preferred because of both maternal and maternal mortality and morbidity. Epidural area has decreased due to pregnancy physiology. Previous studies have shown that the blood given to the epidural area increases the intracranial pressure by compressing the dura mater.Optic nerve diameter measurements ultrasound guided is a non-invasive and reliable method for detecting intracranial pressure increase. In this study, aimed to compare the optic nerve sheath diameter before and after epidural anesthesia with USG.

Detailed description

Epidural anesthesia will be performed at L2 level and sitting position in all patients. Patients will be measured and recorded for optic nerve sheath diameter at 15 min (T2), 30 min (T3) and 60 min (T4) immediately after epidural anesthesia (T0) and after epidural anesthesia.. Measurement of the optic nerve sheath diameter will be done with the help of a linear probe without applying high pressure to the eyeball while the patient is in supine position and the eyelids are closed. The optic nerve sheath diameter will be measured 3 mm beyond the optical disc. The measurements shall be applied in both transverse and sagittal planes for both eyes and the arithmetic mean of the four measured values.

Interventions

PROCEDUREUSG guided ONSD measurement preepidural

Measurement of the diameter of the optic nerve sheath preepidural and postepidural anesthesia

Sponsors

Abant Izzet Baysal University
Lead SponsorOTHER

Study design

Allocation
NON_RANDOMIZED
Intervention model
SEQUENTIAL
Primary purpose
OTHER
Masking
NONE

Eligibility

Sex/Gender
FEMALE
Age
18 Years to 40 Years
Healthy volunteers
Yes

Inclusion criteria

* epidural anesthesia patients * 18-40 years patients * American Society of Anesthesiologists status I-II patients

Exclusion criteria

* Patients with allergy to any of the drugs to be used in the study, * patients with severe heart failure, * atrial and ventricular arrhythmias, * severe valve disease, * electrolyte disorder, * renal failure, preeclampsia, eclampsia

Design outcomes

Primary

MeasureTime frameDescription
increase in the diameter of the optic nerve sheath after epidural anesthesiaBasal(T0),Immediately after administration of epidural anesthesia(T1), after epidural anesthesia 15 min(T2), 30 min (T3),60 min (T4)increase of intracranial pressure as a result of the administration of 20 ml of local anesthetic to the epidural area and its reflection on the diameter of the optic nerve sheath

Contacts

Backup Contactmurat bilgi, MD
Primary Contactmurat bilgi, MD
drmuratbilgi@gmail.com+90 05053745059

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026