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Intravenous Cannulation In Children During Sevoflurane Induction

Intravenous Cannulation In Children During Sevoflurane Induction: Which Time is Adequate

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT03851692
Enrollment
90
Registered
2019-02-22
Start date
2016-08-01
Completion date
2016-12-31
Last updated
2019-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Child, Intravenous Cannulation, Sevoflurane Induction

Keywords

Sevoflurane, Intravenous Cannulation, anesthesia, child

Brief summary

The early placement of an intravenous (iv) line in children anesthetized with halothane has been shown safe and acceptable compared with later placement. However, there's not well known with sevoflurane use (2). The aim of the investigator's study is to determine whether one should make iv attempts during the early induction period (at 60seconds) or lately (90 or 120 s) and waiting until the child receives additional sevoflurane inhalation anesthesia

Detailed description

the investigators conducted a prospective randomized study, after obtaining Institutional review board approval, which didn't require written parental consent. Children age 1-12 years, undergoing elective general anesthesia via an inhalation induction were randomized to one of three groups of 30 patients each one, for iv placement, either 60s (group E), 90 or 120 s (group L) following loss of lid reflex. Movement on iv placement and incidence of laryngospasm were determined. Difficulty with iv placement was also recorded. Statistical analysis included contingency testing, ANOVA, and non parametric testing. A P-value \<0.05 was considered significant.

Interventions

OTHERIntravenous Cannulation (iv placement)

The aim of our study is to determine whether one should make intravenous attempts placement during the early induction period (at 60seconds) or lately (90 or 120 s) and waiting until the child receives additional sevoflurane inhalation anesthesia.

Sponsors

University Hospital Fattouma Bourguiba
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER
Masking
TRIPLE (Subject, Investigator, Outcomes Assessor)

Intervention model description

Prospective randomized single blinded parallel group controlled study

Eligibility

Sex/Gender
ALL
Age
1 Years to 12 Years
Healthy volunteers
No

Inclusion criteria

* ASA I, II * Age from 1 to 12 years old * Ambulatory surgery under general anesthesia.

Exclusion criteria

* Age \<1 year or\> 12 years * non-ambulatory surgery, * contraindication for induction with sevoflurane

Design outcomes

Primary

MeasureTime frameDescription
Movement on iv placementIn the first 5 min after the anesthesic induction with sevofluraneNumber of children who presented movement on iv placement
laryngospasmTime From Intravenous Cannulation to patient extubationThe incidence of laryngospasm

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 19, 2026