Ultrasound Guidance for Embryo Transfer

Transvaginal Versus Transabdominal Ultrasound Guided Embryo Transfer. Randomized Controlled Trial.

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT03851536

Enrollment

178

Registered

2019-02-22

Start date

2016-06-02

Completion date

2019-03-09

Last updated

2019-03-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infertility

Keywords

Embryo Transfer, ICSI, Transvaginal Ultrasound

Brief summary

Randomized controlled study comparing the TVUS versus TAUS guidance during the procedure of embryo transfer.

Detailed description

The aim of this study was to Compare between transvaginal and transabdominal ultrasound guided embryo transfer as regarding clinical pregnancy rate, patient comfort, time required for embryo transfer and endometrial visualization at time of embryo transfer.

Interventions

PROCEDURETransvaginal Ultrasound Guided ET

Use of TVUS to guide ET

PROCEDURETransabdominal Ultrasound Guided ET

Use of TAUS to guide ET

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

SINGLE (Outcomes Assessor)

Eligibility

Sex/Gender

FEMALE

Age

20 Years to 42 Years

Healthy volunteers

Inclusion criteria

All patients undergoing autologous ICSI and frozen embryo transfer (FET) cycles.

Exclusion criteria

1. Cases of sever ovarian hyperstimulation requiring embryo cryopreservation 2. Gestational surrogate cycles 3. Oocyte donation cycles 4. Very poor responders 5. Patients with inadequate visualization of the uterus by ultrasound. 6. Very difficult mock embryo transfer.

Design outcomes

Primary

Measure	Time frame	Description
Clinical pregnancy	3 weeks after Embryo transfer	A clinical pregnancy is a pregnancy that is confirmed by ultrasonic visualization of gestational sac or heartbeat.

Secondary

Measure	Time frame	Description
Time required for ET	Time from when the catheter is handed to the transferring physician to the time it is returned to the transferring embryologist.	Time in seconds required for ET
Degree of cramping and pain	During and immediately after ET	Degree of cramping and pain from 0 to 10 by visual analogue scale (VAS) where 0 is no pain and 10 unbearable pain.
Endometrial visualization at time of embryo transfer	During ET	Endometrial visualization at time of embryo transfer by ultrasound

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026