Bone and Joint Infection
Conditions
Keywords
bone and joint infection, Propionibacterium acnes, Cutibacterium acnes
Brief summary
Osteaoarticular infection due to C. acnes are known to be of late onset, causing chronic infection possibly pauci-symptomatic. Osteaoarticular infection due to C. acnes represents a diagnostic challenge, since C. acnes is slow and difficult to grow, and can also be considered a contaminant.A 16S universal PCR bacteriological diagnosis has been proposed but is lacking of sensitivity. A specific C. acnes PCR was developed in 2010, but is not used routinely.
Interventions
OTHERProsthetic joint infection with Cutibacterium acnes
patients having a prosthesis infection with C.acnes identified by specific PCR
Sponsors
Hospices Civils de Lyon
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 100 Years
Inclusion criteria
* patients having had infection prothesis vith C. acnes identified by PCR
Exclusion criteria
* none
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Rate of diagnostic delay | Outcome is measured at the end of follow-up (usually between 12 and 24 months after antibiotic therapy disruption | time between surgery and detection of C. acnes by PCR |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| rate of radiologic signs | Outcome is measured at the end of follow-up (usually between 12 and 24 months after antibiotic therapy disruption | prosthesis loosening or not |
| rate of duration of antibiotherapy | Outcome is measured at the end of follow-up (usually between 12 and 24 months after antibiotic therapy disruption | measures of duration of the antibiotherapy |
| rate of use of this diagnostic | Outcome is measured at the end of follow-up (usually between 12 and 24 months after antibiotic therapy disruption | descriptions of patients managed with this diagnostic |
Countries
France
Outcome results
None listed