Peanut Allergy
Conditions
Keywords
Peanut Allergy, Skin Prick Test, Oral Food Challenge, Hyponut
Brief summary
The HYPONUT product was previously validated in a laboratory setting (Procédé de préparation d'aliment hypoallergénique, n° FR1250977) on 2012. A international patent was then obtained on 2013. Through the present study, the investigators would like to prove that the hypoallergenicity of the product is sustained in a clinical setting. Patients allergic to peanuts currently undergo in vivo tests to confirm their allergy: skin prick tests, and oral food challenges. In vitro tests are also performed (i.e. IgE levels for peanut and peanut components). The follow-up of patients consists in regular yearly or semestral evaluations. During one of these evaluation, the investigators will skin tests patients with the hyponut product to verify if they are sensitized to this last one as well. When skin tests will be negative, the investigators will propose to patients to take some of the product to verify its tolerability as well.
Interventions
OTHERHyponut
Prick tests with hyponut
Sponsors
University Hospital, Montpellier
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
OTHER
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
6 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patients aged more than 6 * Patients suffering from peanut allergy and followed in the Allergy Unit of the University Hospital of Montpellier (France)
Exclusion criteria
* Pregnancy, or patients breast-feeding * Patients treated with drugs possibly altering the results of the tests (e.g. anti-histamines) * Patients presenting with dermographism * Patients not fluent in French
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Skin Prick Tests evaluation | day patient enrolled |
Secondary
| Measure | Time frame |
|---|---|
| Oral food challenge evaluation | day patient enrolled |
Countries
France
Outcome results
None listed