Dietary Fiber, Dietary Habits, Microbiota, Personalized Advice
Conditions
Keywords
fiber intake, personalized dietary advice, stool pattern, perceived wellbeing
Brief summary
Dietary fibers are linked to improved health and prevention of diseases such as obesity, stroke, hypertension, diabetes and colorectal cancer. Moreover, fibers play a crucial role in improving and maintaining gut health, by increasing stool weight,stool frequency and improvement of stool consistency. Currently, very few adults meet the recommendation of 30 (females) or 40 (males) grams per day. Personalized dietary advice may be the solution to increase dietary fiber intake in large populations. The objective is to investigate if a personalized dietary advice is more effective in increasing dietary fiber intake in the Dutch population than the general advice that is currently provided by the Netherlands Nutrition center and the Dutch Digestive Foundation (MLDS).Second objective is to assess the effect of increased fiber intake on stool pattern, perceived well-being and consumer behavior parameters and the role of psychological factors in the effectiveness of personalized dietary advice on dietary fiber intake. Study design: A 4.5-month (6 weeks intervention + follow-up after 3 months) single-blind randomized controlled trial with two groups: the intervention group, which receives personalized dietary advice (PDA), and the control group, which only receives the general dietary advice. Primary study parameters/outcome of the study: Primary endpoint is dietary fiber intake, which will be assessed using an Food Frequency Questionnaire and 24hr recalls. Fecal microbiota composition and metabolite levels will be used as an objective marker for fiber intake. Secondary study parameters/outcome of the study (if applicable): Secondary parameters include stool pattern, well-being, hunger, satiety and body weight. Furthermore, psychological measurements will give insight into why the PDA was (not) effective.
Detailed description
This study is performed in healthy adults, older than 18 years, with no gastro-intestinal complaints. The intervention group receives personalized dietary advice (PDA) based on their current food pattern, preferences and selfregulation capacity. The PDA aims to compute high-fiber alternatives for products that subjects currently use and that are close to their current eating behavior, to help increase dietary fiber intake. This PDA will be provided using an online webportal. The control group only receives a general dietary advice, e.g. (a) flyer(s) containing information on fibers from the Netherlands Nutrition Center and the MLDS. The intervention group will also receive this general advice next to the PDA.
Interventions
BEHAVIORALPDA
Subjects receive personal dietary fiber advice to increase their fiber intake. This advice will be provided using an online web-portal, where subjects can choose high-fiber alternatives that closely match their own intake. The aim is to swap product for low in fiber for a high fiber alternative (such as white bread, whole wheat bread).
OTHERControl (no intervention)
No intervention
Sponsors
Netherlands: Ministry of Health, Welfare and Sports
Dutch Association for Gastrointestinal diseases (MLDS)
Bolletje
Sensus
Sonneveld
Kellogg Company
Wageningen University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
SINGLE (Subject)
Intervention model description
Two groups: one receives general advice (control), the other personalized advice (intervention). Subjects are followed over time.
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* Age ≥18 years. * Apparently healthy: no gastrointestinal complaints, no food allergies and no medication that can influence the outcome of the study (see
Exclusion criteria
). * Relatively low fiber intake: which is assessed by a short fiber intake screening questionnaire (score ranging from 1 to 22). Females with a score ≤13 and males with a score ≤15 will be included in the study. * Living in the surroundings of Wageningen (max. 50 km). * In possession of a mobile phone with android ≥4.4 or iOS system ≥9 to use apps. * Signed informed consent.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in dietary fiber intake | Before study, after 6 weeks intervention, and 3 months follow-up | Will be measured using the Food Frequency Questionnaire, and 24hr recalls to compute grams of fiber. |
| change in Short Chain Fatty acid level | Before study, at 3 weeks and at 6 weeks | of a fecal sample |
| change in Microbiota composition | Before study, at 3 weeks and at 6 weeks | of a fecal sample |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Hunger and Satiety | Daily during 6-week intervention | Using validated questions |
| Psychological questionnaires | Before and after the 6-week intervention, and at 3-months follow-up | Validated questionnaire will be used to assess motives, barriers, knowledge, intentions, self-efficacy, self-regulation and knowledge |
| Body weight | study start, and after 6 weeks | Subjects weigh themselves (morning, fasted) |
| Stool pattern | Daily during 6-week intervention | Bristol stool chart en stool frequency |
| Perceived wellbeing | Daily during 6-week intervention | Using validated questions |
Countries
Netherlands
Outcome results
None listed