Antibiotic Reaction, Bone and Joint Infection
Conditions
Keywords
cefoxitin, Bone and Joint Infection
Brief summary
Cephamycin related to 2nd generation cephalosporins, the use of cefoxitin has long been limited to antibiotic prophylaxis. Because of its spectrum (sensitive staphylococci, enterobacteria including ESBL, streptococci, anaerobes), its stability and its low cost, it could be useful in curative bone and joint infections, especially in case of infection polymicrobial disease in patients for whom antibiotic alternative per os is limited.
Interventions
OTHERbone and joint infection treated with cefoxitin
the patients had cefoxitin in combination in continuous parenteral administration to treat their bone / joint infection
Sponsors
Hospices Civils de Lyon
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 100 Years
Inclusion criteria
* patients havind had a bon and joint infeciton treated with cefoxitin in combination in continuous parenteral administration
Exclusion criteria
\-
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Rate of Treatment Failure | Outcome is measured at the end of follow-up (usually between 12 and 24 months after antibiotic therapy disruption | Treatment failure is defined by local clinical and/or microbiological relapse; and/or need for additional surgery; death of septic origin |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Rate of use of this strategy | Outcome is measured at the end of follow-up (usually between 12 and 24 months after antibiotic therapy disruption | Descriptions of patients managed with this strategy |
Countries
France
Outcome results
None listed